Results 121 to 130 of about 7,849,545 (341)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Infection rate models for COVID-19: Model risk and public health news sentiment exposure adjustments. [PDF]

PLoS One, 2021
Chalkiadakis I, Yan H, Peters GW, Shevchenko PV.   +3 more
europepmc   +1 more source

Rates of convergence of rho-estimators for sets of densities satisfying shape constraints

, 2016
The purpose of this paper is to pursue our study of rho-estimators built from i.i.d. observations that we defined in Baraud et al. (2014). For a \rho-estimator based on some model S (which means that the estimator belongs to S) and a true distribution of
Baraud, Yannick, Birgé, Lucien
core  

CREDIT RISK. DETERMINATION MODELS [PDF]

Annals of the University of Petrosani: Economics, 2012
The internationalization of financial flows and banking and the rapid development of markets have changed the financial sector, causing him to respond with force and imagination. Under these conditions, the concerns of financial and banking institutions, rating institutions are increasingly turning to find the best solutions to hedge risks and maximize
Mihaela Gruiescu, Mihai Aristotel Ungureanu, Corina Ioanăș   +2 more
openaire   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

A Country Pandemic Risk Exposure Measurement Model

Risk Management and Healthcare Policy, 2020
Simon Grima,1 Murat Kizilkaya,2 Ramona Rupeika-Apoga,3 Inna Romānova,3 Rebecca Dalli Gonzi,4 Mihajlo Jakovljevic5– 7 1Department of Insurance, Faculty of Economics, Management and Accountancy, University of Malta, Msida, Malta; 2Department of ...
Grima S, Kizilkaya M, Rupeika-Apoga R, Romānova I, Dalli Gonzi R, Jakovljevic M   +5 more
doaj  

Appraising prediction research: a guide and meta-review on bias and applicability assessment using the Prediction model Risk Of Bias ASsessment Tool (PROBAST). [PDF]

Nephrology (Carlton), 2021
de Jong Y, Ramspek CL, Zoccali C, Jager KJ, Dekker FW, van Diepen M.   +5 more
europepmc   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Flood Risk Assessment Based on a Cloud Model in Sichuan Province, China [PDF]

, 2023
Jian Liu, Kangjie Wang, Shan Lv, Xiangtao Fan, Haixia He   +4 more
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source