Results 131 to 140 of about 11,903,474 (342)

Numerical Research on Hull–Propeller–Rudder–Ice Interaction of Full-Scale Polar Transport Ship in Brash Ice Channel

open access: yesJournal of Marine Science and Engineering
A strong nonlinear ice load has a significant impact on the resistance and power demand of polar transport ships under different drafts in brash ice channels.
Jinlong Zhang   +4 more
doaj   +1 more source

Trajectory control sensor engineering model detailed test objective [PDF]

open access: yes
The concept employed in an existing Trajectory Control Sensor (TCS) breadboard is being developed into an engineering model to be considered for flight on the Shuttle as a Detailed Test Objective (DTO).
Barr, Joseph Martin, Dekome, Kent
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Numerical Simulation on the Leakage-Induced Collapse of Segmental Tunnels

open access: yesApplied Sciences
Sudden leakage during tunnel construction poses a great threat to the safety of the tunnel. There are relatively few studies on the mechanism of structural collapse induced by tunnel leakage, so it is difficult to propose effective control measures.
Qihao Sun   +3 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

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