Results 131 to 140 of about 11,862,226 (291)
地质科技通报Objective With the construction of reservoir projects, the problem of deformation and instability of colluvial landslides in reservoir areas has become increasingly prominent.
Yilin XU, Yuanyao LI, Side LI, Hao SHI
doaj +1 more source
From previous flume tests conducted in the framework of the OVERCOME Project, intended to investigate the effect of different soil materials, overflow discharges, and upstream face watertightness on the breaching processes of overflowed levee sections, we determined the need for further investigation on the effect of test repeatability, content of ...
Monteiro Alves, Ricardo Manuel +5 more
openaire +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Confidence intervals for the Cox model test error from cross-validation. [PDF]
Stat Med, 2023 Sun MW, Tibshirani R.
europepmc +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Retracted: Model Test and Numerical Simulation of Water Conservancy Foundation Bearing Capacity. [PDF]
Comput Intell Neurosci, 2023 Intelligence And Neuroscience C.
europepmc +1 more source
Independent test of a model to predict severe acute esophagitis [PDF]
, 2017 Bradley, Jeffrey D +5 more
core +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Multiple Intermediary Model Test of Adolescent Physical Exercise and Internet Addiction. [PDF]
Int J Environ Res Public Health, 2023 Qiu C, Qi Y, Yin Y.
europepmc +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source