Results 131 to 140 of about 5,324,413 (319)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Experimental Study on Tunnel Failure Mechanism and the Effect of Combined Anti-Dislocation Measures Under Fault Dislocation

Applied Sciences
Taking the tunnels crossing active faults in China’s Sichuan–Tibet Railway as the research background, experimental studies were conducted using a custom-developed split model box.
Jiaxuan Du, Songhong Yan, Weiyu Sun, Mingxing Cao, Yuxiang Li   +4 more
doaj   +1 more source

Rapid generation of thermal-safe test schedules

, 2005
Overheating has been acknowledged as a major issue in testing complex SOCs. Several power constrained system-level DFT solutions (power constrained test scheduling) have been recently proposed to tackle this problem.
Rosinger, Paul, Chakrabarty, Krishnendu, Krishnendu Chakrabarty, Al-Hashimi, Bashir, Paul Rosinger, Bashir Al-hashimi   +5 more
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Numerical Research on Hull–Propeller–Rudder–Ice Interaction of Full-Scale Polar Transport Ship in Brash Ice Channel

Journal of Marine Science and Engineering
A strong nonlinear ice load has a significant impact on the resistance and power demand of polar transport ships under different drafts in brash ice channels.
Jinlong Zhang, Jianing Zhang, Lei Zhang, Weimin Chen, Qingshan Zhang   +4 more
doaj   +1 more source

Tractor Testing; Drawbar; Caterpillar

, 1940
Crawler tractor being tested. Side view of a Caterpillar steel-tracked crawler diesel (probably a D6 model) being driven on the test track towing the Adams test car and four load tractors. The track at that time was a dirt track, meaning that the surface
Nebraska Tractor Test Laboratory
core  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Tractor Testing; Drawbar Testing; Minneapolis Moline

, 1940
Minneapolis-Moline propane-fueled model during the drawbar test, towing the Adams test car plus load tractors. The two propane cylinders on the first load tractor are used to measure the fuel consumption.
Nebraska Tractor Test Laboratory
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Numerical Simulation on the Leakage-Induced Collapse of Segmental Tunnels

Applied Sciences
Sudden leakage during tunnel construction poses a great threat to the safety of the tunnel. There are relatively few studies on the mechanism of structural collapse induced by tunnel leakage, so it is difficult to propose effective control measures.
Qihao Sun, Xian Liu, Wouter De Corte, Luc Taerwe   +3 more
doaj   +1 more source