Results 71 to 80 of about 24,109,276 (315)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Dynamic Modeling Approach in View of Vector Control and Behavior Analysis of a Multi-Three-Phase Star Permanent Magnet Synchronous Motor Drive

Energies
In order to fully utilize the control degrees of freedom of a multi-three-phase-star smooth-pole permanent magnet synchronous motor (PMSM), this paper first develops a modeling approach using a new matrix transformation method.
Shu Mo, Djamel Ziane, Mouna Oukrid, Mohamed Fouad Benkhoris, Nicolas Bernard   +4 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

UML Sequence Diagram: Transformation from the Two-Hemisphere Model and Layout

Applied Computer Systems, 2013
Modeling of the object interaction is one of the core tasks during system analysis and design, because it gives developer an ability to define responsibilities of class objects and to sketch general architecture of software components.
Nikiforova Oksana, Kozacenko Ludmila, Ahilcenoka Dace   +2 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

The Knowledge Frame System based on Principles of Topological Functioning Model

Applied Computer Systems, 2017
Understanding of domain phenomena and their interrelations is necessary for successful software development. The knowledge frame system based on principles of Topological Functioning Modelling (TFM) can be used for this purpose at the Computation ...
Nazaruks Vladislavs
doaj   +1 more source

Hierarchical Verification for the BPMN Design Model Using State Space Analysis

IEEE Access, 2019
The BPMN design models are widely used in the software development process. Owing to the lack of BPMN standard semantics, formal verification is used to validate whether the BPMN design model is free of undesirable properties.
C. Dechsupa, W. Vatanawood, A. Thongtak
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Applying Model Driven Engineering Techniques and Tools to the Planets Game Learning Scenario

Journal of Interactive Media in Education, 2007
CPM (Cooperative Problem-Based learning Metamodel) is a visual language for the instructional design of Problem-Based Learning (PBL) situations. This language is a UML profile implemented on top of the Objecteering UML Case tool.
Thierry Nodenot, Pierre André Caron, Xavier Le Pallec, Pierre Laforcade   +3 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source