Results 81 to 90 of about 3,690,239 (301)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Simulating Multigraph Transformations Using Simple Graphs [PDF]

open access: yes, 2007
Application of graph transformations for software verification and model transformation is an emergent field of research. In particular, graph transformation approaches provide a natural way of modelling object oriented systems and semantics of object ...
Boneva, Iovka   +3 more
core   +4 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

WSCDL to WSBPEL: A Case Study of ATL-based Transformation [PDF]

open access: yes, 2011
The ATLAS Transformation Language (ATL) is a hybrid transformation language that combines declarative and imperative programming elements and provides means to define model transformations. Most transformations using ATL reported in the literature show a
Ferreira Pires, Luis   +4 more
core   +1 more source

Estimation of a semiparametric transformation model

open access: yes, 2008
This paper proposes consistent estimators for transformation parameters in semiparametric models. The problem is to find the optimal transformation into the space of models with a predetermined regression structure like additive or multiplicative ...
Linton, Oliver   +2 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Transformation of the BPMN Design Model into a Colored Petri Net Using the Partitioning Approach

open access: yesIEEE Access, 2018
Formal verification is a process to ensure that the business process model and notation (BPMN) design model is free of deadlock, livelock, and other undesirable properties that can cause a system crash.
C. Dechsupa, W. Vatanawood, A. Thongtak
doaj   +1 more source

Model transformations and tool integration [PDF]

open access: yesSoftware & Systems Modeling, 2005
Model transformations are increasingly recognised as being of significant importance to many areas of software development and integration. Recent attention on model transformations has particularly focused on the OMGs Queries/Views/Transformations (QVT) Request for Proposals (RFP).
openaire   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Dynamic Modeling Approach in View of Vector Control and Behavior Analysis of a Multi-Three-Phase Star Permanent Magnet Synchronous Motor Drive

open access: yesEnergies
In order to fully utilize the control degrees of freedom of a multi-three-phase-star smooth-pole permanent magnet synchronous motor (PMSM), this paper first develops a modeling approach using a new matrix transformation method.
Shu Mo   +4 more
doaj   +1 more source

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