Results 91 to 100 of about 33,284,612 (360)
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Application of Heuristic Methods for Polymer Synthesis Process Optimization
Journal of EngineeringA numerical algorithm has been developed for solving the problem of finding optimal conditions for the synthesis of polymers using heuristic optimization methods, and its effectiveness has been evaluated in the investigation of the copolymerization ...
Eldar Miftakhov +2 more
doaj +1 more source
Information and Analytical Web Mapping System “Map of Health Care of Krasnoyarsk Region”
MATEC Web of Conferences, 2016 Approaches to the modern geoinformation web-systems development and technological features of software implementation are considered, their development trends are discussed.
Kadochnikov Alexey +2 more
doaj +1 more source
Mathematical Modeling Of Horizontal Displacement Of Above-ground Gas Pipelines [PDF]
, 2017 The modern geodetic equipment allows observations as soon as possible, providing high accuracy and productivity. Achieving high accuracy of measurement is impossible without taking into account external factors that create influence on an observation ...
Kukhtar, D. (Denys)
core
Advanced Cloud Privacy Threat Modeling
, 2016 Privacy-preservation for sensitive data has become a challenging issue in cloud computing. Threat modeling as a part of requirements engineering in secure software development provides a structured approach for identifying attacks and proposing ...
Gholami, Ali, Laure, Erwin
core +1 more source
FEBS Letters, EarlyView.Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa +8 more
wiley +1 more source
Simulation Modeling and Analysis
, 1982 From the Publisher: This second edition of Simulation Modeling and Analysis includes a chapter on "Simulation in Manufacturing Systems" and examples.
Fourth Edition, Averill M. Law
semanticscholar +1 more source
Location Dependent Dirichlet Processes
, 2017 Dirichlet processes (DP) are widely applied in Bayesian nonparametric modeling. However, in their basic form they do not directly integrate dependency information among data arising from space and time.
A Oliva +24 more
core +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source