Results 41 to 50 of about 2,129,256 (356)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Mendel, 2021 3D digitalization of the human body has been studied extensively for various applications in anthropology, ergonomics, healthcare, entertainment and fashion industries.
Dat Tien Nguyen, Thach Ngoc Hoang
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Modeling and Simulation of CNT Using VNL [PDF]
, 2017 Modeling and simulation of metallic are performed through ATK and VNL by quantum wise. The simulation results for the voltage current of length of 17.32 shows more conduction if the length is 21.92 the simulation results for the current voltage shows ...
bala, M. (manju) +2 more
core
Modeling friction: From nanoscale to mesoscale [PDF]
, 2013 The physics of sliding friction is gaining impulse from nanoscale and mesoscale experiments, simulations, and theoretical modeling. This Colloquium reviews some recent developments in modeling and in atomistic simulation of friction, covering open-ended ...
Manini, Nicola +4 more
core +2 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Interdomain I/O Optimization in Virtualized Sensor Networks
Sensors, 2018 In virtualized sensor networks, virtual machines (VMs) share the same hardware for sensing service consolidation and saving power. For those VMs that reside in the same hardware, frequent interdomain data transfers are invoked for data analytics, and ...
Congfeng Jiang +6 more
doaj +1 more source
Summary report of the Simulation Committee [PDF]
, 1977 Topics discussed by the simulation committee included: (1) simulators and their uses; (2) atmospheric disturbance modeling requirements; (3) Status of simulators' capabilities for modeling disturbances; and (4) status of atmospheric disturbance models ...
Kurkowski, R. L.
core +1 more source
A General Simulation Framework for Supply Chain Modeling: State of the Art and Case Study
, 2010 Nowadays there is a large availability of discrete event simulation software that can be easily used in different domains: from industry to supply chain, from healthcare to business management, from training to complex systems design.
Cimino, Antonio +2 more
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source