Results 41 to 50 of about 703,031 (245)

3D Reconstruction Human Body From Anthropometric Measurements Using Diversity Control Oriented Genetic Algorithm

open access: yesMendel, 2021
3D digitalization of the human body has been studied extensively for various applications in anthropology, ergonomics, healthcare, entertainment and fashion industries.
Dat Tien Nguyen, Thach Ngoc Hoang
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Interdomain I/O Optimization in Virtualized Sensor Networks

open access: yesSensors, 2018
In virtualized sensor networks, virtual machines (VMs) share the same hardware for sensing service consolidation and saving power. For those VMs that reside in the same hardware, frequent interdomain data transfers are invoked for data analytics, and ...
Congfeng Jiang   +6 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Adjoint and Unrolled Automatic Differentiation for Laplace‐Approximated Likelihoods in Population PK and PK/PD Models

open access: yesCPT: Pharmacometrics & Systems Pharmacology
Maximum likelihood estimation in population pharmacokinetic/pharmacodynamic (PK/PD) nonlinear mixed‐effects (NLME) models targets fixed‐effect, interindividual‐variability, and residual‐variability parameters through a marginal likelihood that integrates
Guido H. Jajamovich   +3 more
doaj   +1 more source

Cycle Network Model of Prostaglandin H Synthase-1

open access: yesPharmaceuticals, 2020
The kinetic model of Prostaglandin H Synthase-1 (PGHS-1) was developed to investigate its complex network kinetics and non-steroidal anti-inflammatory drugs (NSAIDs) efficacy in different in vitro and in vivo conditions. To correctly describe the complex
Alexey Goltsov   +3 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Delta3D: a complete open source game and simulation engine for building military training systems [PDF]

open access: yes, 2006
Dela3D, the open source game and simulation engine built for military training, in continuing to be improved to meet the requirements of the military users.
McDowell, Perry   +3 more
core   +2 more sources

VPMBench: a test bench for variant prioritization methods

open access: yesBMC Bioinformatics, 2021
Background Clinical diagnostics of whole-exome and whole-genome sequencing data requires geneticists to consider thousands of genetic variants for each patient.
Andreas Ruscheinski   +3 more
doaj   +1 more source

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