Results 81 to 90 of about 2,129,256 (356)
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Scientific Reports, 2018 Nano-structured superlattices may have novel physical properties and irradiation is a powerful mean to drive their self-organization. However, the formation mechanism of superlattice under irradiation is still open for debate.
Yipeng Gao +6 more
doaj +1 more source
RPPM : Rapid Performance Prediction of Multithreaded workloads on multicore processors [PDF]
, 2019 Analytical performance modeling is a useful complement to detailed cycle-level simulation to quickly explore the design space in an early design stage. Mechanistic analytical modeling is particularly interesting as it provides deep insight and does not ...
Akram, Shoaib +3 more
core +2 more sources
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
The role of primitive part modelling within an integrative simulation environment [PDF]
, 2003 The component-based modeling approach to the simulation of HVAC systems has been in used for many years. The approach not only supports plant simulation but also allows the integration of the building and plant domains.
Chow, T.T., Clarke, J.A., Song, C.L.
core
Modeling and Simulation of Liquid Crystal Elastomers
, 2010 We consider a continuum model describing the dynamic behavior of nematic liquid crystal elastomers (LCEs) and implement a numerical scheme to solve the governing equations. In the model, the Helmholtz free energy and Rayleigh dissipation are used, within
Palffy-Muhoray, Peter +2 more
core +1 more source
Simulation of econometric models [PDF]
Proceedings of the 6th conference on Winter simulation, 1973 The purposes of this tutorial are to present some fundamental properties of econometric model structures relevant to effective understanding of simulation procedures, and to describe the use of simulation software for analysis and forecasting.The fundamental concepts of model specification are developed formally to provide a logical foundation for ...
openaire +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Models, Simulations, and Experiments [PDF]
, 2002 I discuss the difference between models, simulations, and experiments from an epistemological and an ontological perspective. I first distinguish between “static” models (like a map) and “dynamic” models endowed with the capacity to generate processes. Only the latter can be used to simulate.
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Modeling and simulation with INSIGHT [PDF]
Proceedings of the 18th conference on Winter simulation - WSC '86, 1986 The INSIGHT simulation language describes systems in a quick, simple, and compact fashion using a network representation. This description can be entered and simulated using novel interactive facilities that relieve the user of needing to know specific syntax, while promoting a greater understanding of model behavior.
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