Results 41 to 50 of about 2,072 (266)

Application of georadars for detecting subsurface defects in layers of non-rigid road pavements

Вісник Харківського національногоуніверситету імені В.Н. Каразіна. Серія: Радіофізика та електроніка, 2020
The relevance of the problem under consideration is a consequence of the high cost of classical methods of pavement inspection. At the same time, the use of modern pulse georadars allows to ensure a relatively low cost of monitoring the current state of ...
D. O. Batrakov, M. S. Antyufeyeva, A. G. Batrakova   +2 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Soft computing applications in asphalt pavement: A comprehensive review of data-driven techniques using response surface methodology and machine learning

Journal of Road Engineering
The asphalt pavement industry is transforming because of the growing influence of artificial intelligence and industrial digitization. As a result of this shift, there is a stronger emphasis on advanced statistical approaches like optimization tools like
Nura Shehu Aliyu Yaro, Muslich Hartadi Sutanto, Mohd Rosli Hainin, Noor Zainab Habib, Aliyu Usman, Muhammad Sani Bello, Surajo Abubakar Wada, Abiola Usman Adebanjo, Ahmad Hussaini Jagaba   +8 more
doaj   +1 more source

Prediction of temperatures within the depth of asphalt concrete layers and the modeling of temperature-dependent parameters for flexible road pavements design purposes [PDF]

Дороги і мости
Introduction. The introduction to the paper highlights the aspects of the analysis of results of flexible road pavement load test which shall be related to the temperature-dependent characteristics of asphalt concrete. Problem statement. The issues of
Tetyana Tereshchenko
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Evaluation and Study of Prestressed Slab Structure Precast Modular Concrete

Media Komunikasi Teknik Sipil, 2020
Prestressed precast modular concrete slabs function rigid pavement, supporting vehicle loads above it on subgrade with relatively low bearing capacity. This slab measures 2000 x 850 x 150 mm3 of regular reinforced concrete (old production) or prestressed
I Gusti Lanang Bagus Eratodi, Ali Awaludin, Ay Lie Han, Andreas Triwiyono   +3 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Permanent deformation of unbound granular materials: A review

Journal of Traffic and Transportation Engineering (English ed. Online)
Several studies have been conducted in the pavement area to try to understand the elastoplastic behavior of unbound granular materials (UGMs) under cyclic loading.
Hugo Alexander Rondón-Quintana, Juan Gabriel Bastidas-Martínez, Fredy Alberto Reyes-Lizcano   +2 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source