Results 51 to 60 of about 6,328,246 (251)

Resource Oriented Modelling: Describing Restful Web Services Using Collaboration Diagrams

open access: yes, 2011
The popularity of Resource Oriented and RESTful Web Services is increasing rapidly. In these, resources are key actors in the interfaces, in contrast to other approaches where services, messages or objects are. This distinctive feature necessitates a new
Alowisheq, Areeb   +2 more
core   +1 more source

service-oriented approach for interactive computing systems

open access: yesPublicaciones en Ciencias y Tecnología, 2011
The introduction of new technologies leads to a more and more complex interactive systems design. In order to describe the future interactive system, the human computer interaction domain uses specific models, design processes and tools in order to ...

doaj  

Review of the Statistical methods used in original articles Published in Iranian Journal of Public Health: 2015-2019

open access: yesIranian Journal of Public Health, 2021
Background: Nowadays, statistical methods are used frequently in research articles. This review study aimed to determine the statistical methods used in original articles published in Iranian journal of public health (IJPH). Methods: Original articles
Sajjad Bahariniya, Farzan Madadizadeh
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Time trend and geographical distribution of major depressive disorder in Iran, 1990 to 2021: results from the Global Burden of Disease Study

open access: yesBMJ Open
Objective Major depressive disorder (MDD) is a disabling disease and is recognised as a serious, public health concern. In this study, we aimed to determine the burden and trends of MDD in Iran.Design and participants Secondary data from the Global ...
Moslem Taheri Soodejani   +1 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Estimated public health impact of concurrent mask mandate and vaccinate-or-test requirement in Illinois, October to December 2021

open access: yesBMC Public Health
Background Facing a surge of COVID-19 cases in late August 2021, the U.S. state of Illinois re-enacted its COVID-19 mask mandate for the general public and issued a requirement for workers in certain professions to be vaccinated against COVID-19 or ...
François M. Castonguay   +13 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Impact-acceleration head injury results in optic neuropathy in the thirteen-lined ground squirrel

open access: yesCommunications Biology
Traumatic brain injury (TBI) caused by rapid head acceleration produces visual impairments from damage to the optic nerve (ON), as well as widespread perturbations of the central visual system.
Francisco M. Nadal-Nicolás   +6 more
doaj   +1 more source

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