Results 71 to 80 of about 6,328,246 (251)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2018 Introduction: Childhood cansers are the second leading cause of death among children. Since the incidence and prevalence of malignancies are different in different regions and there are several cultural and environmental factors involved, the aim of this
Mostafa Eghbalian +5 more
doaj
Sensors, 2016 The service of sensor device in Emerging Sensor Networks (ESNs) is the extension of traditional Web services. Through the sensor network, the service of sensor device can communicate directly with the entity in the geographic environment, and even impact
Feng Zhang, Yuetong Xu, Jarong Chou
doaj +1 more source
Software-as-a-Service Revenue Models [PDF]
IT Professional, 2013 This paper give an overview of the three main revenue models, focusing on the advantages and disadvantages for SaaS providers and their customers. Also identify the most effective revenue model for particular situations.
openaire +3 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Management of Teaching Hospitals; Opportunities and Threats [PDF]
Strides in Development of Medical Education, 2016 Background & Objective: The plan of integration of medical schools into the health system was adopted in 1985 and one of its consequences was the creation of the teaching hospital The aim of this study was to investigate the problems and challenges of ...
Mohammad Reza Amiresmaili +5 more
doaj
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Consumer handbook for vocational rehabilitation services. 2012: Oct.
, 2003 Title from PDF cover (viewed May 18, 2007).; "May 2003."; This handbook is designed to provide general information about the vocational rehabilitation program offered through the Connecticut Dept.
Connecticut. Bureau of Rehabilitation Services.
core +1 more source
Annual report/ Connecticut Department of Revenue Services. FY 2015-2016.
, 2016 Annual; Fiscal years 2003/2004 and 2004/2005 combined.; Report year ends June 30.; Prepared by the Dept.
Connecticut. Department of Revenue Services.
core