Results 71 to 80 of about 5,613,073 (287)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Are you using the right tools in computational electromagnetics?
Engineering Reports, 2019 Have you ever wondered why we use certain computational electromagnetics methods and how we decide on the choice of tools for modeling problems in electromagnetics?
Krishnaswamy Sankaran
doaj +1 more source
Supplemental data acquisition tools for modeling environmental systems
Revista de Matemática: Teoría y Aplicaciones, 2009 The goal of our on-going research is to develop effective and reliable tools for modeling the environmental systems of the Gulf of Mexico. For example, our on-going research into methodologies for the prediction of water levels in the shallow waters of ...
Carl W. Steidley +2 more
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Visual Modeling Tools for Problem-Based Learning for Teaching High School Programming
Современные информационные технологии и IT-образование, 2020 This article is dedicated to the developing of methodology for teaching high school students computer science disciplines like algorithms and programming, using a problem-based learning with visual modeling tools.
Sergei Kostousov, Irina Simonova
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
A framework for evaluating tool support for co-evolution of modeling languages, tools and models [PDF]
We present a framework for evaluating language workbenches’ capabilities for co-evolution of graphical modeling languages, modeling tools and models. As with programming, maintenance tasks such as language refinement and enhancement typically account for
Pierantonio, Alfonso +5 more
core +1 more source
Evaluating Image-Based Interactive 3D Modeling Tools
IEEE AccessStructure from Motion (SfM) is a computer vision technique used to reconstruct three-dimensional (3D) structures from a series of two-dimensional (2D) images or video frames.
Arslan Siddique +3 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
SDLcheck: A Model Checking Tool [PDF]
, 2001 SDLcheck is a verification tool developed to support model checking for asynchronous (concurrent) programs written in SDL 1, 2. Given an SDL program and a specification of a desired behavior of the program, SDLcheck generates a verification model that consists of two .-automata, P and T : P models the program and T the specification.
Vladimir Levin, Hüsnü Yenigün
openaire +2 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source