Results 101 to 110 of about 1,160,554 (311)

Sparse Decomposition and Modeling of Anatomical Shape Variation [PDF]

IEEE Transactions on Medical Imaging, 2007
Recent advances in statistics have spawned powerful methods for regression and data decomposition that promote sparsity, a property that facilitates interpretation of the results. Sparse models use a small subset of the available variables and may perform as well or better than their full counterparts if constructed carefully.
Sjöstrand K, Rostrup E, Ryberg C, Larsen R, Studholme C, Baezner H, Ferro J, Fazekas F, PANTONI, LEONARDO, INZITARI, DOMENICO, Waldemar G, LADIS Study Group   +11 more
openaire   +7 more sources

Clinical significance of stratifying prostate cancer patients through specific circulating genes

Molecular Oncology, EarlyView.
We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian, Edouard Jarry, Arynne Santos, Quentin Vesval, Lucie Hamel, Rafael Sanchez‐Salas, Alexis Rompré‐Brodeur, Wassim Kassouf, Raghu Rajan, Fadi Brimo, Marie Duclos, Armen Aprikian, Simone Chevalier   +12 more
wiley   +1 more source

Finite element analysis of titanium anatomic plate and titanium reconstructive plate for treatment of extra-articular fractures of the scapula

Journal of Orthopaedic Surgery and Research, 2023
Background Due to the lack of postoperative reporting outcomes and bio-mechanical studies, an optimal management of scapular fractures has not been well-established in clinical treatment, even though there are many options available.
Yanliang Shang, Yunlong Bi, Yang Cao, Yansong Wang   +3 more
doaj   +1 more source

Anatomically informed Bayesian spatial priors for fMRI analysis [PDF]

arXiv, 2019
Existing Bayesian spatial priors for functional magnetic resonance imaging (fMRI) data correspond to stationary isotropic smoothing filters that may oversmooth at anatomical boundaries. We propose two anatomically informed Bayesian spatial models for fMRI data with local smoothing in each voxel based on a tensor field estimated from a T1-weighted ...
arxiv  

Integrating Genomic Knowledge Sources through an Anatomy Ontology [PDF]

, 2004
Modern genomic research has access to a plethora of knowledge sources. Often, it is imperative that researchers combine and integrate knowledge from multiple perspectives.
Gennari, John H, Silberfein, Adam, Wiley, Jesse   +2 more
core   +1 more source

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

Molecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric, Annika Auranen, Katrin Kleinmanns, René DePont Christensen, Liv Cecilie Vestrheim Thomsen, Cara Ellen Wogsland, Emmet McCormack, Johanna Mäenpää, Kristine Madsen, Karen Stampe Petersson, Mansoor Raza Mirza, Line Bjørge   +11 more
wiley   +1 more source

Clinical outcomes in neovascular age-related macular degeneration: a cohort study of patients with care delay due to the COVID-19 pandemic

Scientific Reports, 2023
The COVID-19 pandemic has led to both intentional and unintentional care delay among age-related neovascular macular degeneration (nvAMD) patients. Prior studies have demonstrated that patients who discontinue nvAMD treatment for prolonged intervals are ...
Timothy M. Janetos, Roya Zandi, David Younessi, Gina Johnson, Amber Randolph, Manjot Gill   +5 more
doaj   +1 more source

The Anatomic Pathology Hospitalist Model

Archives of Pathology & Laboratory Medicine
Context.— Challenges to staffing a high-quality frozen section service include consolidation of health systems and pathology practices, off-campus relocation of some pathology offices, growing numbers of stand-alone surgery centers, and subspecialization among pathologists and surgeons.
Ellen E, Chapel, David B, Chapel, L Priya, Kunju, John A, Hamilton, Jeffrey L, Myers, Liron, Pantanowitz   +5 more
openaire   +2 more sources

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

Molecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh, Amelia Martinez Villarreal, Philippe Lefrançois, Jennifer Gantchev, Sriraam Sivachandran, Samy Abou Setah, Ivan V. Litvinov   +6 more
wiley   +1 more source

An alternative experimental model for training in microsurgery

Revista do Colégio Brasileiro de Cirurgiões
OBJECTIVE: to describe a new model of training in microsurgery with pig spleen after splenectomy performed by undergraduate students of the Discipline of Operative Technique of the UFPR Medical School.
Ivan Maluf Junior, Alfredo Benjamin Duarte Da Silva, Anne Karoline Groth, Marlon Augusto Camara Lopes, Adriana Sayuri Kurogi, Renato Da Silva Freitas, Flávio Daniel Saavedra Tomasich   +6 more
doaj   +1 more source