Results 11 to 20 of about 3,102,841 (203)

Codimension-two bifurcations in animal aggregation models with symmetry [PDF]

open access: yes, 2014
Pattern formation in self-organized biological aggregation is a phenomenon that has been studied intensively over the past 20 years. In general, the studies on pattern formation focus mainly on identifying the biological mechanisms that generate these ...
Hillen T.   +2 more
core   +3 more sources

Research Models for Studying Vascular Calcification [PDF]

open access: yes, 2020
Calcification of the vessel wall contributes to high cardiovascular morbidity and mortality. Vascular calcification (VC) is a systemic disease with multifaceted contributing and inhibiting factors in an actively regulated process.
Babic, Milen   +4 more
core   +1 more source

Advantages and Progress of Using Chinese Hamsters to Construct Disease Models

open access: yesShiyan dongwu yu bijiao yixue, 2021
Chinese hamsters are experimental animals originally from China. They play an important role in experimental research on medicine and biology. They are widely used in life science research, such as genetics, infectious diseases, tissue culture ...
GAO Jiping   +4 more
doaj   +1 more source

Lymphoma caused by intestinal microbiota. [PDF]

open access: yes, 2014
The intestinal microbiota and gut immune system must constantly communicate to maintain a balance between tolerance and activation: on the one hand, our immune system should protect us from pathogenic microbes and on the other hand, most of the millions ...
Schiestl, Robert H, Yamamoto, Mitsuko L
core   +2 more sources

Mathematical modelling in animal nutrition: a centenary review [PDF]

open access: yes, 2008
A centenary review presents an opportunity to ponder over the processes of concept development and give thought to future directions. The current review aims to ascertain the ontogeny of current concepts, underline the connection between ideas and people
A. DUMAS   +95 more
core   +2 more sources

Animal Models of GWAS-Identified Type 2 Diabetes Genes [PDF]

open access: yes, 2013
More than 65 loci, encoding up to 500 different genes, have been implicated by genome-wide association studies (GWAS) as conferring an increased risk of developing type 2 diabetes (T2D).
Bellomo, EA   +4 more
core   +1 more source

TARM1 contributes to development of arthritis by activating dendritic cells through recognition of collagens

open access: yesNature Communications, 2021
TARM1 is a LILR family member that drives cell signalling via interactions with FcRγ. Here the authors show that TARM1 binds collagens to activate dendritic cells and thereby is an effector of inflammatory arthritis, plus provide a soluble TARM-Fc fusion
Rikio Yabe   +10 more
doaj   +1 more source

Generation of a homozygous RANGRF knockout hiPSC line by CRISPR/Cas9 system

open access: yesStem Cell Research, 2023
The RAN Guanine Nucleotide Release Factor (RANGRF) gene encodes the protein MOG1, which binds to Nav1.5 and facilitates its transport to the cell membrane. Nav1.5 mutations have been linked to various cardiac arrhythmias and cardiomyopathy.
Meiling Jiang   +7 more
doaj   +1 more source

Validating Animal Models [PDF]

open access: yes, 2015
This paper responds to a recent challenge for the validity of extrapolation of neurobiological knowledge from laboratory animals to humans. According to this challenge, experimental neurobiology, and thus neuroscience, is in a state of crisis because the
Atanasova, Nina
core   +6 more sources

1st INCF Workshop on Genetic Animal Models for Brain Diseases [PDF]

open access: yes, 2011
The INCF Secretariat organized a workshop to focus on the “role of neuroinformatics in the processes of building, evaluating, and using genetic animal models for brain diseases” in Stockholm, December 13–14, 2009.
Holm Graessner, Olaf Riess
core   +2 more sources

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