Results 121 to 130 of about 1,977,773 (318)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Models of Biological Pattern Formation [PDF]
, 2007 Models of Biological Pattern ...
Hans Meinhardt
core
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
BiomoleculesPharmacological antidepressant treatments alter the molecular and functional reactivity of stress-sensitive neural networks. However, how classical versus rapid-acting antidepressants differentially modulate acute stress-induced transcriptional responses
Veronica Begni +7 more
doaj +1 more source
Modeling, and estimation for biological Plants
Modélisation, et estimation pour des systèmes biologiques L'estimation de l'état d'un système dynamique est une étape cruciale, que ce soit pour la synthèse d'un contrôleur ou simplement pour l'identification ou la surveillance des processus.
openaire +3 more sources
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
On engineering reliability concepts and biological aging [PDF]
Some stochastic approaches to biological aging modeling are studied. We assume that an organism acquires a random resource at birth. Death occurs when the accumulated dam-age (wear) exceeds this initial value, modeled by the discrete or continuous random
Maxim S. Finkelstein
core
Chemical and biological phosphorus removal in the activated sludge process [PDF]
, 1980 Bibliography: leaves 86-88.This investigation set out to establish in what degree the phosphorus removal characteristics of the Modified Activated Sludge Process could be enhanced by the in-plant addition of iron salts.
Rabinowitz, Barry
core
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source