Results 51 to 60 of about 30,009,286 (350)

Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack, Wan‐Chun Chang, Miguel Cordova‐Delgado, Spencer J. Anderson, Jessica N. Trueman, Erika N. Scott, Catrina M. Loucks, Shahrad R. Rassekh, Gabriella S. S. Groeneweg, Michelle Higginson, Kathy Li, Fudan Miao, Derek Yau, Donna Johnston, Mounira Ibrahim, Maja Krajinovic, Thai Hoa Tran, Jessica Tewfik, Jean‐François Bussières, Thaïna‐Rafi Jean‐Baptiste, Denis Lebel, Lucie Pecheux, Bina Gyawali, Gregory Guilcher, Gesche Riabowol, Geert ’t Jong, Michelle Staub, Geoff Cuvelier, Kathleen Felton, Sara Khalaj, Michael Rieder, Awatif Abuzgaia, Tamorah Lewis, Himal Ghimire, Paul Nathan, Kerry Goralski, Ketan Kulkarni, Zara Forbrigger, Colin J. D. Ross, Bruce C. Carleton   +39 more
wiley   +1 more source

Sodium benzoate may reduce appetite in Drosophila melanogaster through serotonin upregulation [PDF]

Archives of Biological Sciences
Sodium benzoate is a common artificial preservative in processed food, yet little is known about its long-term health effects. Since sodium benzoate could upregulate serotonin, we hypothesized that it may induce satiety and activate processes underlying ...
Nas John Sylvester B., Medina Paul Mark B.   +1 more
doaj   +1 more source

Kinetic hierarchy and propagation of chaos in biological swarm models [PDF]

, 2011
We consider two models of biological swarm behavior. In these models, pairs of particles interact to adjust their velocities one to each other. In the first process, called 'BDG', they join their average velocity up to some noise.
Aoki, B. Wennberg, Balmforth, Bertin, Bertin, Bolley, Carlen, Carlen, Carrillo, Cercignani, Chuang, Couzin, Cucker, Degond, Degond, Degond, Desvillettes, Diaconis, E. Carlen, Graham, Hillen, Illner, Janvresse, Kac, Lachowicz, Lanford, Maslen, McKean, Mogilner, P. Degond, Painter, R. Chatelin, Sznitman, Topaz, Vicsek   +34 more
core   +4 more sources

MYCN Amplification in RB1‐Inactivated Retinoblastoma: Association With High‐Risk Features

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background MYCN amplification occurs in a subset of retinoblastoma cases, both with and without RB1 inactivation. It has been suggested that retinoblastomas with MYCN amplification represent a distinct entity with more aggressive clinical behavior.
Kyriaki Papaioannou, Regina Kubica, Karen Fischhuber, Jasmin Beygo, Madlen Reschke, Petra Ritter‐Sovinz, Eva Biewald, Petra Ketteler, Dietmar Lohmann, Deniz Kanber   +9 more
wiley   +1 more source

The lees extracts of Philippine rice wine (Tapuy) protect transgenic Caenorhabditis elegans from glyphosate-induced neurotoxicity

Food Production, Processing and Nutrition
Tapuy is an indigenous rice wine traditionally prepared during rituals and ceremonies in the northern regions of the Philippines. Its fermentation by-product, the Tapuy lees, is nutrient-dense but is underutilized for human consumption.
Junelle Rey C. Bacong, Mark Joseph R. Remucal, Paul Mark B. Medina   +2 more
doaj   +1 more source

Peptimapper: proteogenomics workflow for the expert annotation of eukaryotic genomes

BMC Genomics, 2019
Background Accurate structural annotation of genomes is still a challenge, despite the progress made over the past decade. The prediction of gene structure remains difficult, especially for eukaryotic species, and is often erroneous and incomplete.
Laetitia Guillot, Ludovic Delage, Alain Viari, Yves Vandenbrouck, Emmanuelle Com, Andrés Ritter, Régis Lavigne, Dominique Marie, Pierre Peterlongo, Philippe Potin, Charles Pineau   +10 more
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Neurotoxic and neuromotor effects of cyanate, an oxidative byproduct of cyanide from linamarin in cassava: A systematic review

NAJFNR
Background Linamarin-induced neurotoxicity manifests as either polyneuropathy, ataxia, and sensorineural deafness or as isolated symmetric spastic paraparesis of bilateral limbs, which are frequently observed in populations subsisting on a monotonous ...
Rafael Vincent Manalo, Antonio Lorenzo Ong, Paul Mark Medina   +2 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Slow-Freezing Cryopreservation Ensures High Ovarian Tissue Quality Followed by In Vivo and In Vitro Methods and Is Safe for Fertility Preservation

Medicina, 2020
Background and objectives: Cancer incidence is growing with younger patients diagnosed with this disease every year. Improved cancer diagnostics and treatment lead to better survival of cancer patients.
Živilė Gudlevičienė, Kastytis Žilinskas, Gabrielis Kundrotas, Monika Grubliauskaitė, Daiva Baltriukienė, Virginija Bukelskienė   +5 more
doaj   +1 more source