Results 51 to 60 of about 3,620,832 (281)

Quantitative analysis of regulatory flexibility under changing environmental conditions [PDF]

, 2010
The circadian clock controls 24-h rhythms in many biological processes, allowing appropriate timing of biological rhythms relative to dawn and dusk. Known clock circuits include multiple, interlocked feedback loops.
Adrian W Thomson, Alexandra Pokhilko, Andrew J Millar, David A Rand, Dunlap JC, Ferenc Nagy, Kieron D Edwards, Kirsten Knox, Laszlo Kozma‐Bognar, Ozgur E Akman, Paul E Brown, Peter J Lumsden, Thomas B   +12 more
core   +4 more sources

Peptimapper: proteogenomics workflow for the expert annotation of eukaryotic genomes

BMC Genomics, 2019
Background Accurate structural annotation of genomes is still a challenge, despite the progress made over the past decade. The prediction of gene structure remains difficult, especially for eukaryotic species, and is often erroneous and incomplete.
Laetitia Guillot, Ludovic Delage, Alain Viari, Yves Vandenbrouck, Emmanuelle Com, Andrés Ritter, Régis Lavigne, Dominique Marie, Pierre Peterlongo, Philippe Potin, Charles Pineau   +10 more
doaj   +1 more source

Relation of Adverse Childhood Experiences to Clinical and Patient‐Reported Outcomes for Adults With Sickle Cell Disease: A Registry Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adverse childhood experiences (ACEs) are stressful or traumatic events prior to age 18 that are known to have a lasting impact on individuals’ health and well‐being. There is a gap in understanding the relationship between ACEs and Other Life Stressors and health status for adults with sickle cell disease (SCD).
Marsha Treadwell, Jessica Liang, Liliana Preiss, Angela Rivers, Jane S. Hankins, Allison King, Justin Williams, Michael B. Potter, Danielle Hessler   +8 more
wiley   +1 more source

A Mathematical Framework for Agent Based Models of Complex Biological Networks [PDF]

, 2010
Agent-based modeling and simulation is a useful method to study biological phenomena in a wide range of fields, from molecular biology to ecology. Since there is currently no agreed-upon standard way to specify such models it is not always easy to use ...
A. S. Jarrah, A. Veliz-Cuba, Abdul Salam Jarrah, David Murrugarra, F. Castiglione, Franziska Hinkelmann, G. U. Y. Pe’er, I. Shmulevich, M. Gardner, M. Pogson, R. Laubenbacher, R. Lidl, R. Thomas, Reinhard Laubenbacher, S. Eubank, S. Hardy, V. Grimm, Z. Wang   +17 more
core   +1 more source

Parasites as biological models

Parasitology, 1969
The value of metazoan parasites as models for the investigation of fundamental biological phenomena is discussed. The fields in which they are of particular value include: immunology, neuromuscular physiology, nucleo-cytoplasmic relationships, genetics, cyto-differentiation, comparative biochemistry.After reviewing some examples of experimental ...
openaire   +2 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Analysis of a Model Biological Switch [PDF]

SIAM Journal on Applied Mathematics, 1985
A model mechanism proposed by the second author [On pattern formation mechanisms for lepidopteran wing patterns and mammalian coat markings. Philos. Trans. R. Soc. Lond., B 295, 473-496 (1981)] for generating wing patterns and eyespots on butterflies and moths is based on a morphogen (S) activated biological switch for a gene product (g).
Kath, W. L., Murray, J. D.
openaire   +2 more sources

Slow-Freezing Cryopreservation Ensures High Ovarian Tissue Quality Followed by In Vivo and In Vitro Methods and Is Safe for Fertility Preservation

Medicina, 2020
Background and objectives: Cancer incidence is growing with younger patients diagnosed with this disease every year. Improved cancer diagnostics and treatment lead to better survival of cancer patients.
Živilė Gudlevičienė, Kastytis Žilinskas, Gabrielis Kundrotas, Monika Grubliauskaitė, Daiva Baltriukienė, Virginija Bukelskienė   +5 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Realistic Models of Biological Motion

, 1998
The origin of biological motion can be traced back to the function of molecular motor proteins. Cytoplasmic dynein and kinesin transport organelles within our cells moving along a polymeric filament, the microtubule.
Ajdari, Ajdari, Ajdari, Astumian, Astumian, Cooke, Cooke, Doering, Edman, Eisenberg, Faucheux, Faucheux, Finer, Gilbert, Goldman, Harada, Hill, Hirose, Hoenger, Hunt, Huxley, Huxley, Imre Derényi, Katz, Kikkawa, Kron, Kull, Leibler, Lymn, Magnasco, Millonas, Millonas, Pate, Pate, Rayment, Rousselet, Sablin, Sleep, Svoboda, Svoboda, Svoboda, Tamás Vicsek, Vale   +42 more
core   +1 more source