Results 41 to 50 of about 1,317,332 (190)

What Genetic Modifications of Source Pigs Are Essential and Sufficient for Cell, Tissue, and Organ Xenotransplantation?

Transplant International
Xenotransplantation of porcine organs has made remarkable progress towards clinical application. A key factor has been the generation of genetically multi-modified source pigs for xenotransplants, protected against immune rejection and coagulation ...
Asghar Ali, Asghar Ali, Mayuko Kurome, Mayuko Kurome, Barbara Kessler, Barbara Kessler, Elisabeth Kemter, Elisabeth Kemter, Elisabeth Kemter, Elisabeth Kemter, Eckhard Wolf, Eckhard Wolf, Eckhard Wolf, Eckhard Wolf   +13 more
doaj   +1 more source

Patient and Disease-Specific Induced Pluripotent Stem Cells for Discovery of Personalized Cardiovascular Drugs and Therapeutics. [PDF]

, 2020
Human induced pluripotent stem cells (iPSCs) have emerged as an effective platform for regenerative therapy, disease modeling, and drug discovery.
Chandy, Mark, Paik, David T, Wu, Joseph C   +2 more
core  

The genetics of cardiovascular disease [PDF]

, 2008
Recent advances in genotyping technology and insights into disease mechanisms have increased interest in the genetics of cardiovascular disease. Several candidate genes involved in cardiovascular diseases were identified from studies using animal models,
Abu-Amero, Aitman, Anna F. Dominiczak, Benhamou, Bhatnagar, Bowcock, Caulfield, Chen, Christian Delles, Clark, Conrad, Cowley, Cupples, Delles, Delles, Delles, Dominiczak, Dominiczak, Dutil, Edwards, Emilsson, Garrett, Good, Graham, Grunfeld, Gunderson, Guzik, Hamilton, Hamilton, Harrap, Hunt, Iwai, Jakubowska, Jeffs, Jeffs, Ji, Kathiresan, Kerr, Klein, Latronico, Levy, Martin W. McBride, Matarín, Matarín, Matsuzaki, McBride, McBride, McCarthy, Monti, Moreno, Mueller, Newhouse, Oniki, Padmanabhan, Padmanabhan, Petretto, Pollex, Rapp, Roodi, Samani, Sandhu, Sandosh Padmanabhan, Sayed-Tabatabaei, Sharma, Staessen, Teo, Tobin, Tobin, Turner, Wallace, Wilson, Zalba, Zimmerli   +72 more
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Modeling risks of cardiovascular and cancer mortality following a diagnosis of loco-regional breast cancer

Breast Cancer Research, 2021
Background Many women with breast cancer also have a high likelihood of cardiovascular mortality, and while there are several cardiovascular risk prediction models, none have been validated in a cohort of breast cancer patients.
Nicole M. Leoce, Zhezhen Jin, Rebecca D. Kehm, Janise M. Roh, Cecile A. Laurent, Lawrence H. Kushi, Mary Beth Terry   +6 more
doaj   +1 more source

Zebrafish models of cardiovascular disease

Heart Failure Reviews, 2016
Cardiovascular disease (CVD) is one of the leading causes of death worldwide. The most significant risk factors associated with the development of heart diseases include genetic and environmental factors such as hypertension, high blood cholesterol levels, diabetes, smoking, and obesity.
Despina Bournele, Dimitris Beis
openaire   +3 more sources

Partial CFD models of cardiovascular stents [PDF]

, 2002
Copyright @ 2002 Wiley BlackwellThis paper outlines the use of a partial CFD stent model in order to improve discretisation of important small features. The effects of mesh size on the performance measure are investigated.
Atherton, MA, Tesch, K
core  

Feline Hypertrophic Cardiomyopathy: A Spontaneous Large Animal Model of Human HCM. [PDF]

, 2017
Hypertrophic cardiomyopathy (HCM) is a common disease in pet cats, affecting 10-15% of the pet cat population. The similarity to human HCM, the rapid progression of disease, and the defined and readily determined endpoints of feline HCM make it an ...
Freeman, Lisa M, Huggins, Gordon S, Maron, Martin S, Rush, John E, Stern, Joshua A   +4 more
core   +2 more sources

Cysteine Leukotriene Receptor Antagonist—Montelukast—Treatment Improves Experimental Abdominal Aortic Aneurysms in Mice

Cardiovascular Therapeutics
Conclusion: Montelukast treatment improves experimental nondissected AAAs in mice partly by improving aortic inflammation.
Kexin Li, Meng Li, Panpan Wei, Kangli Tian, Haole Liu, Weilai Fu, Haiwen Hou, Yajie Chen, Baohui Xu, Yankui Li, Sihai Zhao   +10 more
doaj   +1 more source

G-Protein coupled receptor signalling in pluripotent stem cell-derived cardiovascular cells: Implications for disease modelling [PDF]

, 2015
Human pluripotent stem cell derivatives show promise as an in vitro platform to study a range of human cardiovascular diseases. A better understanding of the biology of stem cells and their cardiovascular derivatives will help to understand the strengths
Dolatshad, NF, Foldes, G, Harding, SE, Hellen, N, Jabbour, R   +4 more
core   +1 more source

Medium reach theory for nursing in cardiovascular rehabilitation

Revista Brasileira de Enfermagem, 2021
Objectives: to describe a medium-range nursing theory for the cardiovascular rehabilitation process. Methods: theoretical development study, addressing the elaboration of medium-range theory, based on Roy’s Adaptation Model, which combined theoretical ...
Maria Sinara Farias, Lúcia de Fátima da Silva, Marcos Antônio Gomes Brandão, Maria Vilani Cavalcante Guedes, Keila Maria de Azevedo Pontes, Rafael Oliveira Pitta Lopes   +5 more
doaj   +2 more sources