Results 41 to 50 of about 23,798,154 (337)

Relationship between the triglyceride-glucose index and risk of cardiovascular diseases and mortality in the general population: a systematic review and meta-analysis

Cardiovascular Diabetology, 2022
Background The triglyceride-glucose (TyG) index is a new alternative measure for insulin resistance. This meta-analysis was conducted to assess the associations of the TyG index with the risks of cardiovascular diseases and mortality in the general ...
Xiao Liu, Ziqi Tan, Yuna Huang, Huilei Zhao, Menglu Liu, P. Yu, Jianyong Ma, Yujie Zhao, Wengen Zhu, Jingfeng Wang   +9 more
semanticscholar   +1 more source

Function and distribution of circulating human PCSK9 expressed extrahepatically in transgenic mice

Journal of Lipid Research, 2009
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is predominantly expressed in liver and regulates cholesterol metabolism by down regulating liver LDL receptor (LDLR) proteins.
Yi Luo, Laurie Warren, Donghui Xia, Heather Jensen, Thomas Sand, Stephen Petras, Wenning Qin, Kenneth S. Miller, Julie Hawkins   +8 more
doaj   +1 more source

Creating Fair Models of Atherosclerotic Cardiovascular Disease Risk [PDF]

, 2019
Guidelines for the management of atherosclerotic cardiovascular disease (ASCVD) recommend the use of risk stratification models to identify patients most likely to benefit from cholesterol-lowering and other therapies.
Coulet, Adrien, Marafino, Ben, Palaniappan, Latha, Pfohl, Stephen, Rodriguez, Fatima, Shah, Nigam H.   +5 more
core   +4 more sources

Animal Models of Cardiovascular Diseases [PDF]

BioMed Research International, 2011
Cardiovascular diseases are the first leading cause of death and morbidity in developed countries. The use of animal models have contributed to increase our knowledge, providing new approaches focused to improve the diagnostic and the treatment of these pathologies.
Zaragoza, Carlos, Gomez-Guerrero, Carmen, Martin-Ventura, Jose Luis, Blanco-Colio, Luis, Lavín Plaza, Begoña, Mallavia, Beñat, Tarin, Carlos, Mas, Sebastian, Ortiz, Alberto, Egido, Jesus   +9 more
openaire   +3 more sources

Machine learning in precision diabetes care and cardiovascular risk prediction

Cardiovascular Diabetology, 2023
Artificial intelligence and machine learning are driving a paradigm shift in medicine, promising data-driven, personalized solutions for managing diabetes and the excess cardiovascular risk it poses.
E. Oikonomou, Rohan Khera
semanticscholar   +1 more source

Plasma lipidomic signatures of spontaneous obese rhesus monkeys

Lipids in Health and Disease, 2019
Background Obesity plays crucial roles in the pathogenesis of metabolic diseases such as hyperlipidemia, nonalcoholic fatty liver disease (NAFLD), and type 2 diabetes (T2D).
Junlong Wang, Linqiang Zhang, Ruyue Xiao, Yunhai Li, Shasha Liao, Zhiguo Zhang, Wenhui Yang, Bin Liang   +7 more
doaj   +1 more source

Multifaceted Functions and Novel Insight Into the Regulatory Role of RNA N6-Methyladenosine Modification in Musculoskeletal Disorders

Frontiers in Cell and Developmental Biology, 2020
RNA modifications have emerged as key regulators of transcript expression in diverse physiological and pathological processes. As one of the most prevalent types of RNA modifications, N6-methyladenosine (m6A) has become the highlight in modulation of ...
Wenchao Zhang, Wenchao Zhang, Lile He, Lile He, Zhongyue Liu, Zhongyue Liu, Xiaolei Ren, Xiaolei Ren, Lin Qi, Lin Qi, Lu Wan, Lu Wan, Wanchun Wang, Wanchun Wang, Chao Tu, Chao Tu, Zhihong Li, Zhihong Li   +17 more
doaj   +1 more source

Cardiovascular disease and air pollution in Scotland: no association or insufficient data and study design? [PDF]

, 2012
<p><b>Background:</b> Coronary heart disease and stroke are leading causes of mortality and ill health in Scotland, and clear associations have been found in previous studies between air pollution and cardiovascular disease. This study
Bhaskar, A., Brewster, D., Chalmers, J., Fischbacher, C., Lee, D., Morris, G., Ramsay, C., Scott, E.M., Willocks, L.   +8 more
core   +1 more source

Triglyceride-glucose index, renal function and cardiovascular disease: a national cohort study

Cardiovascular Diabetology, 2023
Background The triglyceride-glucose (TyG) index is a predictor of cardiovascular diseases; however, to what extent the TyG index is associated with cardiovascular diseases through renal function is unclear.
Cancan Cui, Lin Liu, Te Zhang, Ling Fang, Zhanhao Mo, Yitian Qi, Jia Zheng, Zhijia Wang, Haikun Xu, Han Yan, Siqi Yue, Xuekui Wang, Zhiyuan Wu   +12 more
semanticscholar   +1 more source

Association of Mental Health-Related Proteins DAXX, DRD3, and DISC1 With the Progression and Prognosis of Chondrosarcoma

Frontiers in Molecular Biosciences, 2019
Chondrosarcoma is the second most common malignant bone tumor. Current therapies remain ineffective, resulting in poor prognoses. Biomarkers for chondrosarcoma and predictors of its prognosis have not been established. Mental health–related proteins have
Lile He, Lile He, Xiangyu Shi, Ruiqi Chen, Ruiqi Chen, Zhengchun Wu, Zhulin Yang, Zhihong Li, Zhihong Li   +8 more
doaj   +1 more source