Results 51 to 60 of about 2,739,180 (294)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Spectral models of stellar populations resolved in chemical abundances

, 2011
We present model spectra of stellar populations with variable chemical composition. We derived the [alpha/Fe] abundance ratio of the stars of the most important libraries (ELODIE, CFLIB and MILES) using full spectrum fitting and we generated PEGASE.HR ...
Koleva, Mina, Prugniel, Philippe
core   +1 more source

Goldstone boson counting in linear sigma models with chemical potential [PDF]

, 2005
We analyze the effects of finite chemical potential on spontaneous breaking of internal symmetries within the class of relativistic field theories described by the linear sigma model.
A. Beraudo, H. Georgi, I. Schur, J. Goldstone, Tomáš Brauner   +4 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Chemical enrichment in very low-metallicity environments: Bootes I [PDF]

, 2014
We present different chemical evolution models for the ultrafaint dwarf galaxy Bootes I. We either assume that the galaxy accretes its mass through smooth infall of gas of primordial chemical composition (classical models) or adopt mass accretion ...
Bellazzini, Michele, Leaman, Ryan, Romano, Donatella, Starkenburg, Else   +3 more
core   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Potential role of senescent macrophages in radiation-induced pulmonary fibrosis

Cell Death and Disease, 2021
Radiation-induced pulmonary fibrosis (RIPF) is a late toxicity of therapeutic radiation in clinic with poor prognosis and limited therapeutic options. Previous results have shown that senescent cells, such as fibroblast and type II airway epithelial cell,
Lulu Su, Yinping Dong, Yueying Wang, Yuquan Wang, Bowen Guan, Yanhua Lu, Jing Wu, Xiaochun Wang, Deguan Li, Aimin Meng, Feiyue Fan   +10 more
doaj   +1 more source

Model Discrimination in Chemical Kinetics [PDF]

The Open Catalysis Journal, 2009
In studies on chemical kinetics, generally after the rate data have been taken, a mechanism and an associated rate law model are proposed based on the data taken. Frequently, more than one mechanism and rate law may be consis- tent with data. In order to find the correct rate law, regression techniques (model discrimination) are applied to indentify ...
Özdemir, Burcu, Gültekin, Selahattin
openaire   +1 more source

Fermion determinants in matrix models of QCD at nonzero chemical potential [PDF]

, 1997
The presence of a chemical potential completely changes the analytical structure of the QCD partition function. In particular, the eigenvalues of the Dirac operator are distributed over a finite area in the complex plane, whereas the zeros of the ...
A. D. Jackson, A. D. Jackson, A. D. Jackson, A. Gocksch, A. Ukawa, C. DeTar, E. V. Shuryak, F. Butler, F. Haake, H. J. Sommers, I. M. Barbour, J. B. Kogut, J. Ginibre, J. J. M. Verbaarschot, J. J. M. Verbaarschot, J. J. M. Verbaarschot, J. J. M. Verbaarschot, J. Vink, M. A. Halasz, M. F. L. Golterman, M. Halasz, M. Stephanov, M. Stephanov, N. Bilic, N. Bilic, P. E. Gibbs, P. E. Gibbs, P. H. Damgaard, P. H. Damgaard, R. A. Janik, R. A. Janik, S. J. Hands, T. Banks, T. Wettig, V. Matveev, Y. Fyodorov   +35 more
core   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source