Results 61 to 70 of about 1,158,124 (312)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Stratospheric ozone in 3-D models: A simple chemistry and the cross-tropopause flux [PDF]
, 2000 Two simple and computationally efficient models for simulating stratospheric ozone in three-dimensional global transport models are presented. The first, linearized ozone (or Linoz), is a first-order Taylor expansion of stratospheric chemical rates in ...
McLinden, C. A +17 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Integrated Decision Support for Assessing Chemical Liabilities
, 2011 Chemical liabilities, such as adverse effects and toxicity, have a major impact on today's drug discovery process. In silk prediction of chemical liabilities is an important approach which can reduce costs and animal testing by complementing or replacing
Carlsson, Lars +9 more
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
The Platelet as a Model for Chemical Genetics [PDF]
Chemistry & Biology, 2003 Chemical genetics is an emerging strategy in chemical biology that promises to bring the power of true genetics to mammalian systems and facilitate the transfer of biological discoveries to therapeutics. The platelet is an anucleate cell with several features that render it suitable for chemical genetic analysis.
Flaumenhaft, Robert, Sim, Derek S
openaire +2 more sources
Potential role of senescent macrophages in radiation-induced pulmonary fibrosis
Cell Death and Disease, 2021 Radiation-induced pulmonary fibrosis (RIPF) is a late toxicity of therapeutic radiation in clinic with poor prognosis and limited therapeutic options. Previous results have shown that senescent cells, such as fibroblast and type II airway epithelial cell,
Lulu Su +10 more
doaj +1 more source
Theory of Chemical Kinetics and Charge Transfer based on Nonequilibrium Thermodynamics
, 2013 Advances in the fields of catalysis and electrochemical energy conversion often involve nanoparticles, which can have kinetics surprisingly different from the bulk material.
Bazant, Martin Z.
core +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
SET-THEORETIC DESCRITPION OF FUNCTIONAL MODELS OF CHEMICAL MANUFACTURING
Тонкие химические технологии, 2017 The technique for the formalized description of functional models of chemical manufacturing is developed. The technique is based on graph theory.
E. V. Burlyaeva +2 more
doaj +1 more source