Results 81 to 90 of about 1,158,124 (312)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Models of necessity

open access: yesBeilstein Journal of Organic Chemistry, 2020
The way chemists represent chemical structures as two-dimensional sketches made up of atoms and bonds, simplifying the complex three-dimensional molecules comprising nuclei and electrons of the quantum mechanical description, is the everyday language of ...
Timothy Clark, Martin G. Hicks
doaj   +1 more source

Screening chemical kinetic models: Collision limit violations and ultra-fast time scales

open access: yes, 2019
Detailed chemical kinetic models are widely used in combustion research and many new mechanisms for different fuels and reacting conditions are developed and published each year.
Im, Hong G.   +3 more
core  

A General Overview of Mesenchymal Stem Cell Therapies in Drug- and Chemical-Induced Liver Injury Models [PDF]

open access: yes
Liver injury is commonly seen in the population depending on the drug and chemical usage. Different groups of drugs and chemicals lead to different pathogeneses in the liver, such as necrosis, fibrosis, or inflammation.
Suna Ömeroğlu   +2 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Construção de modelos para ilustração de estruturas moleculares em aulas de química

open access: yesQuímica Nova, 1999
This paper describes the construction of a kit of molecular model for illustration of molecular structure in chemical class using cheap materials. The atoms were represented by plastic spheres and the bonds between the atoms were made from plastic straws
Lima M. B., Lima-Neto P. De
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Mathematical modeling for digestible protein in animal feeds for tilapia

open access: yesRevista Brasileira de Zootecnia, 2012
The objective of this study was to formulate mathematical models to estimate digestible protein in some animal feeds for tilapia. Literature results of the proximate composition of crude protein, ether extract, and mineral matter, as well as digestible ...
Luiz Vítor Oliveira Vidal   +5 more
doaj   +1 more source

Application of mathematical models in chemical engineering research, design, and production : proceedings of symposium no. 4 held on 14 and 15 June 1965.

open access: yes, 1965
"Organised by the American Institute of Chemical Engineers & the Institution of Chemical Engineers."Includes bibliographical ...
American Institute of Chemical Engineers.   +2 more
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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