Results 71 to 80 of about 2,739,180 (294)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2020 The way chemists represent chemical structures as two-dimensional sketches made up of atoms and bonds, simplifying the complex three-dimensional molecules comprising nuclei and electrons of the quantum mechanical description, is the everyday language of ...
Timothy Clark, Martin G. Hicks
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Construção de modelos para ilustração de estruturas moleculares em aulas de química
Química Nova, 1999 This paper describes the construction of a kit of molecular model for illustration of molecular structure in chemical class using cheap materials. The atoms were represented by plastic spheres and the bonds between the atoms were made from plastic straws
Lima M. B., Lima-Neto P. De
doaj
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Mathematical modeling for digestible protein in animal feeds for tilapia
Revista Brasileira de Zootecnia, 2012 The objective of this study was to formulate mathematical models to estimate digestible protein in some animal feeds for tilapia. Literature results of the proximate composition of crude protein, ether extract, and mineral matter, as well as digestible ...
Luiz Vítor Oliveira Vidal +5 more
doaj +1 more source
The mass-metallicity relation of tidal dwarf galaxies
, 2015 Dwarf galaxies generally follow a mass-metallicity (MZ) relation, where more massive objects retain a larger fraction of heavy elements. Young tidal dwarf galaxies (TDGs), born in the tidal tails produced by interacting gas-rich galaxies, have been ...
Kroupa, P., Ploeckinger, S., Recchi, S.
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Revista Mexicana de NeurocienciaObjective: The objective of this study was to evaluate the neurotoxicity and neuroprotective activity of cannabidiol (CBD), valproate, furosemide, metformin, and bilobalide, individually and mixed with CBD in PC12 cells exposed to Glutamate. In addition,
Jesús Vélez-Huerta +4 more
doaj