Intersection Between Local Anesthetics and Cancer Biology: What Now? Where Are We Going?
Local anesthetics (LAs), widely used in anesthesia, may also play a role in cancer treatment by inhibiting tumor growth, reducing metastasis, and enhancing immune responses. They modulate key pathways like AKT/mTOR and RAS/ERK while affecting angiogenesis and tumor innervation and the immune response.
Eduardo Nunez‐Rodriguez+3 more
wiley +1 more source
Editorial: AI's transformative role in neuro-intervention: enhancing diagnosis and treatment strategies. [PDF]
Chen S+5 more
europepmc +1 more source
Infrared (IR) light evokes distinct calcium and water transport responses in astrocytes, depending on stimulation duration and protocol. This study uses widefield imaging and pharmacology to reveal differential engagement of astroglial signaling pathways.
Wilson R. Adams+7 more
wiley +1 more source
Facial expression deep learning algorithms in the detection of neurological disorders: a systematic review and meta-analysis. [PDF]
Yoonesi S+14 more
europepmc +1 more source
Beyond Order: Perspectives on Leveraging Machine Learning for Disordered Materials
This article explores how machine learning (ML) revolutionizes the study and design of disordered materials by uncovering hidden patterns, predicting properties, and optimizing multiscale structures. It highlights key advancements, including generative models, graph neural networks, and hybrid ML‐physics methods, addressing challenges like data ...
Hamidreza Yazdani Sarvestani+4 more
wiley +1 more source
Editorial: Neurobiological underpinnings of neurodegenerative and neuropsychiatric disorders: from models to therapy. [PDF]
Di Cunto F+5 more
europepmc +1 more source
Patient‐specific brain phantoms can replace animal trials, aid presurgical training, and enable in silico disease research on cerebrospinal fluid and ventricles. This study presents a method to create ventricular brain phantoms from three‐dimensional magnetic resonance images brain scans, resulting in durable, tunable, reproducible models that mimic ...
Kajal Chandraprakash Jain+3 more
wiley +1 more source
Stem Cells in Large Animal Models of Retinal and Neurological Disease
Henry Klassen+4 more
doaj +1 more source
Preface to the special issue on: "Preclinical common data elements for epilepsy research part II of the TASK3 group of the ILAE/AES Joint Translational Task Force". [PDF]
Galanopoulou AS.
europepmc +1 more source
A Novel Approach to Implementing Artificial Thalamic Neurons with Ferroelectric Transistors
Artificial neurons created using CMOS technology often require a large number of transistors and capacitors. This study introduces an artificial thalamic neuron that employs only five CMOS compatible ferroelectric transistors. The manufactured thalamic neuron demonstrates leaky integrate‐and‐fire‐or‐burst (LIFB) functionalities, featuring self ...
Andreas Grenmyr+7 more
wiley +1 more source