Results 261 to 270 of about 1,748,144 (308)

Neuropathogenesis of Old World Alphaviruses: Considerations for the Development of Medical Countermeasures. [PDF]

Viruses
Lantz AM, Baxter VK.
europepmc   +1 more source

Neural Plasticity and Hearing‐Speech Development in Children with Auditory Brainstem Implants for Congenital Hearing Loss Due to Severe Inner Ear Malformation

Advanced Science, EarlyView.
Data from a prospective cohort with 112 auditory brainstem implant users are analyzed. Younger age at implantation (<3 years), less severe inner‐ear malformation (common cavity, cochlear aplasia, and hypoplasia), and more intraoperative eABR evoked electrodes (≥60%) are associated with better hearing and speech outcomes.
Yu Zhang, Yongchuan Chai, Yiwen Zhang, Huan Jia, Zhaoyan Wang, Zhihua Zhang, Zhili Wang, Jie Chen, Xue Wang, Yun Li, Ying Chen, Hao Wu   +11 more
wiley   +1 more source

Plasma proteomic signatures as predictors of dementia risk in individuals with sleep apnea: a cohort study. [PDF]

Transl Neurodegener
Liu Y, Gao PY, Wang Z, Li R, Meng K, Le W, Tang Y.   +6 more
europepmc   +1 more source

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

Advanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao, Jiayu Lu, Quanjun Yang, Zhenqi Liu, Cuiping Wu, Bingbing Ke, Kaiyan Su, Haolin Yuan, Yaqi Cui, Yao Wang, Richard Salvi, Guang Yang, Shankai Yin, Feng Liu, Chunyan Li   +14 more
wiley   +1 more source

Mitochondrial unfolded protein response (UPR^mt) as novel therapeutic targets for neurological disorders. [PDF]

J Cereb Blood Flow Metab
Chen X, An H, He J, Guo J, Xu S, Wu C, Wu D, Ji X.   +7 more
europepmc   +1 more source

RONIN/HCF1‐TFEB Axis Protects Against D‐Galactose‐Induced Cochlear Hair Cell Senescence Through Autophagy Activation

Advanced Science, EarlyView.
D‐galactose (D‐gal) induced inner ear hair cell senescence by inhibiting TFEB transcription. RONIN/HCF1 promotes TFEB transcription to prevent cochlear HCs from D‐gal‐induced senescence through autophagy activation. Abstract Age‐related hearing loss is characterized by senescent inner ear hair cells (HCs) and reduced autophagy.
Yongjie Wei, Yuhua Zhang, Wei Cao, Nan Cheng, Yun Xiao, Yongjun Zhu, Yan Xu, Lei Zhang, Lingna Guo, Jun Song, Su‐hua Sha, Buwei Shao, Fang Ma, Jingwen Yang, Zheng Ying, Zuhong He, Renjie Chai, Qiaojun Fang, Jianming Yang   +18 more
wiley   +1 more source

Spine plasticity to restore the cortical networks of movement: a therapeutic approach to spinal cord injury. [PDF]

Brain Commun
Machado C, Hollis E.
europepmc   +1 more source

Consequences and Mechanisms of Noise‐Induced Cochlear Synaptopathy and Hidden Hearing Loss, With Focuses on Signal Perception in Noise and Temporal Processing

Advanced Science, EarlyView.
Noise‐induced synaptopathy (NIS) is largely reversible due to self‐repair. NIS and noise‐induced hidden hearing loss are two concepts with similarities and differences. The major hearing deficits in NIHHL are temporal processing disorders. The translation of animal data in NIS studies to humans is hindered by many factors.
Hui Wang, Steven J Aiken, Jian Wang
wiley   +1 more source

The equity neuroscience journal's declaration. [PDF]

Equity Neurosci
Orjuela KD, Ortiz-Garcia J.
europepmc   +1 more source

Machine learning models in the prediction of chronic or shunt-dependent hydrocephalus following subarachnoid hemorrhage: A systematic review and meta-analysis.

Neuroradiol J
Hajikarimloo B, Mohammadzadeh I, Habibi MA, Tos SM, Asgarzadeh A, Tajvidi M, Aghajani S, Hashemi R, Kooshki A.   +8 more
europepmc   +1 more source