Results 41 to 50 of about 32,339,977 (323)

Lymphocryptovirus-dependent occurrence of lymphoma in SIV-infected rhesus macaques with particular consideration to two uncommon cases of non-Hodgkin's lymphoma [PDF]

open access: yesPrimate Biology, 2016
Despite combination antiretroviral therapy, high-grade malignant non-Hodgkin's lymphoma (NHL) is still one of the most frequently acquired immunodeficiency syndrome (AIDS)-defining disorders in the end stage of infection with human immunodeficiency virus
A. Klippert   +8 more
doaj   +1 more source

brms: An R Package for Bayesian Multilevel Models Using Stan

open access: yes, 2017
The brms package implements Bayesian multilevel models in R using the probabilistic programming language Stan. A wide range of distributions and link functions are supported, allowing users to fit - among others - linear, robust linear, binomial, Poisson,
P. Bürkner
semanticscholar   +1 more source

MODELING MODELING [PDF]

open access: yesJournal of the Experimental Analysis of Behavior, 1999
Models are tools; they need to fit both the hand and the task. Presence or absence of a feature such as a pacemaker or a cascade is not in itself good. Or bad. Criteria for model evaluation involve benefit‐cost ratios, with the numerator a function of the range of phenomena explained, goodness of fit, consistency with other nearby models, and ...
openaire   +2 more sources

Influence of sperm cryopreservation on sperm motility and proAKAP4 concentration in mice

open access: yesReproductive Medicine and Biology, 2022
Background The protein proAKAP4 is crucial for sperm motility and has been suggested as an indicator of male fertility. We determined the relationship between proAKAP4 concentration and sperm motility parameters in mice, and investigated the effects of ...
Auke Boersma   +8 more
doaj   +1 more source

lmerTest Package: Tests in Linear Mixed Effects Models

open access: yes, 2017
One of the frequent questions by users of the mixed model function lmer of the lme4 package has been: How can I get p values for the F and t tests for objects returned by lmer?
Alexandra Kuznetsova   +2 more
semanticscholar   +1 more source

To model or not to model?

open access: yesMolecular Biology of the Cell, 2011
In theory, the combination of mathematical modeling with experimental studies can be a powerful and compelling approach to understanding cell biology. In practice, choosing appropriate problems, identifying willing and able collaborators, and publishing the resulting research can be remarkably challenging.
openaire   +4 more sources

Controlling the uncontrolled variation in the diet induced obese mouse by microbiomic characterization

open access: yesScientific Reports, 2022
Group sizes in an animal study are calculated from estimates on variation, effect, power and significance level. Much of the variation in glucose related parameters of the diet-induced obese (DIO) mouse model is due to inter-individual variation in gut ...
Valeriia Bondarenko   +9 more
doaj   +1 more source

Modeling Modeling

open access: yes, 2009
Model-driven engineering and model-based approaches have permeated all branches of software engineering; to the point that it seems that we are using models, as Molière's Monsieur Jourdain was using prose, without knowing it. At the heart of modeling, there is a relation that we establish to represent something by something else.
Muller, Pierre-Alain   +2 more
openaire   +3 more sources

Ultrasound imaging for assessing aortic phenotypes: A preclinical tool for measuring cardiac disease model progression and therapeutic effect

open access: yesWFUMB Ultrasound Open
Cardiac dysfunction is a common feature of numerous diseases, ranging from metabolic disorders like Mucopolysaccharidosis Type 1 (MPS I), a.k.a. Hurler syndrome to neuromuscular disorders such as Myotonic Dystrophy type 1 (DM1).
James Cao   +8 more
doaj   +1 more source

Revisiting a quarter of a century of simian immunodeficiency virus (SIV)-associated cardiovascular diseases at the German Primate Center [PDF]

open access: yesPrimate Biology, 2017
Human immunodeficiency virus (HIV) comorbidities have become clinically more important due to antiretroviral therapy. Although therapy increases life expectancy, it does not completely suppress immune activation and its associated complications.
M. Mietsch   +8 more
doaj   +1 more source

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