Results 101 to 110 of about 92,121 (267)

Perturbative unitarity violation in radiative capture transitions to dark matter bound states

Journal of High Energy Physics
We investigate the formation of bound states of non-relativistic dark matter particles subject to long-range interactions through radiative capture.
Martin Beneke, Tobias Binder, Lorenzo De Ros, Mathias Garny, Stefan Lederer   +4 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Holographic Dark Matter and Higgs Models [PDF]

Physical Review Letters, 2008
We propose a dark matter candidate within the class of models where electroweak symmetry breaking is triggered by a light composite Higgs boson. In these dual anti-de Sitter/conformal field theory models, the Higgs boson emerges as a holographic pseudo-Goldstone boson, while dark matter can be identified with a stable composite fermion X0.
openaire   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Revisiting the decoupling limit of the Georgi-Machacek model with a scalar singlet

Journal of High Energy Physics
We study the connection between collider and dark matter phenomenology in the singlet extension of the Georgi-Machacek model. In this framework, the singlet scalar serves as a suitable thermal dark matter (DM) candidate. Our focus lies on the region v χ <
Geneviève Bélanger, Juhi Dutta, Rohini M. Godbole, Sabine Kraml, Manimala Mitra, Rojalin Padhan, Abhishek Roy   +6 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Left-right Model for Dark Matter

Communications in Physics, 2018
We argue that dark matter can automatically arise from a gauge theory that possesses a non-minimal left-right gauge symmetry, SU(3)_C \otimes SU(M)_L \otimes SU(N)_R \otimes U(1)_X, for (M,N)=(2,3), (3,2), (3,3), \cdots, and (5,5).
Dong, P. V., Huong, D. T.
openaire   +3 more sources

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Low-energy radiative backgrounds in CCD-based dark-matter detectors

Journal of High Energy Physics
The reach of sub-GeV dark-matter detectors is at present severely affected by low-energy events from various origins. We present the theoretical methods to compute the single- and few-electron events that arise from secondary radiation emitted by high ...
Peizhi Du, Daniel Egaña-Ugrinovic, Rouven Essig, Mukul Sholapurkar   +3 more
doaj   +1 more source