Results 71 to 80 of about 137,955 (315)
A new LHC search for dark matter produced via heavy Higgs bosons using simplified models [PDF]
, 2023 D. Pérez Adán +5 more
openalex +1 more source
Search for Invisible Axion Dark Matter with the Axion Dark Matter Experiment. [PDF]
Physical Review Letters, 2018 This Letter reports the results from a haloscope search for dark matter axions with masses between 2.66 and 2.81 μeV. The search excludes the range of axion-photon couplings predicted by plausible models of the invisible axion.
N. Du +27 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Search for WIMPs at future μ + μ + colliders
Journal of High Energy PhysicsWeakly interacting massive particles (WIMPs) with electroweak charges, such as the wino and the Higgsino, stand out as natural candidates for dark matter in the universe. In this paper, we study the search for WIMPs at future multi-TeV μ + μ + colliders.
Hajime Fukuda +3 more
doaj +1 more source
Electroweak symmetry breaking and WIMP-FIMP dark matter
Journal of High Energy Physics, 2022 Electroweak Symmetry Breaking (EWSB) is known to produce a massive universe that we live in. However, it may also provide an important boundary for freeze-in or freeze-out of dark matter (DM) connected to Standard Model via Higgs portal as processes ...
Subhaditya Bhattacharya +2 more
doaj +1 more source
Constraints on warm dark matter from UV luminosity functions of high-z galaxies with Bayesian model comparison [PDF]
, 2021 Anton Rudakovskyi +3 more
openalex +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Ultralight scalars as cosmological dark matter [PDF]
, 2016 Many aspects of the large-scale structure of the Universe can be described successfully using cosmological models in which 27±1% of the critical mass-energy density consists of cold dark matter (CDM).
L. Hui +3 more
semanticscholar +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source