Results 71 to 80 of about 902,528 (341)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Effective field theory and scalar triplet dark matter

Journal of High Energy Physics
We discuss an extension of the standard model with a real scalar triplet, T, including non-renormalizable operators (NROs) up to d = 6. If T is odd under a Z 2 symmetry, the neutral component of T is a good candidate for the dark matter (DM) of the ...
Carolina Arbeláez, Marcela González, Martin Hirsch, Nicolás A. Neill, Diego Restrepo   +4 more
doaj   +1 more source

Revisiting simplified dark matter models in terms of AMS-02 and Fermi-LAT

, 2017
We perform an analysis of the simplified dark matter models in the light of cosmic ray observables by AMS-02 and Fermi-LAT. We assume fermion, scalar or vector dark matter particle with a leptophobic spin-0 mediator that couples only to Standard Model ...
Li, Tong
core   +1 more source

Phenomenological models of dark energy interacting with dark matter [PDF]

, 2015
An interaction between dark matter and dark energy is usually introduced by a phenomenological modification of the matter conservation equations, while the Einstein equations are left unchanged.
Nicola Tamanini
semanticscholar   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Probing dark matter particles at CEPC

, 2019
We investigate the capability of the future electron collider CEPC in probing the parameter space of several dark matter models, including millicharged dark matter models, $Z'$ portal dark matter models, and effective field theory dark matter models.
Liu, Zuowei, Xu, Yong-Heng, Zhang, Yu
core   +1 more source

Indirect Dark Matter Signatures in the Cosmic Dark Ages I. Generalizing the Bound on s-wave Dark Matter Annihilation from Planck [PDF]

, 2015
Recent measurements of the cosmic microwave background (CMB) anisotropies by Planck provide a sensitive probe of dark matter annihilation during the cosmic dark ages, and specifically constrain the annihilation parameter $f_\mathrm{eff} \langle \sigma v \
Slatyer, Tracy R.
core   +2 more sources

Extended Search for the Invisible Axion with the Axion Dark Matter Experiment. [PDF]

Physical Review Letters, 2019
This Letter reports on a cavity haloscope search for dark matter axions in the Galactic halo in the mass range 2.81-3.31  μeV. This search utilizes the combination of a low-noise Josephson parametric amplifier and a large-cavity haloscope to achieve ...
T. Braine, R. Cervantes, N. Crisosto, N. Du, S. Kimes, L. Rosenberg, G. Rybka, J. Yang, D. Bowring, A. Chou, R. Khatiwada, A. Sonnenschein, W. Wester, G. Carosi, N. Woollett, L. Duffy, R. Bradley, C. Boutan, M. Jones, B. LaRoque, N. Oblath, M. Taubman, J. Clarke, A. Dove, A. Eddins, S. O'kelley, S. Nawaz, I. Siddiqi, N. Stevenson, A. Agrawal, A. Dixit, J. Gleason, S. Jois, P. Sikivie, J. Solomon, N. Sullivan, D. Tanner, E. Lentz, E. Daw, J. Buckley, P. M. Harrington, E. Henriksen, K. Murch   +42 more
semanticscholar   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

General Analysis of Antideuteron Searches for Dark Matter

, 2010
Low energy cosmic ray antideuterons provide a unique low background channel for indirect detection of dark matter. We compute the cosmic ray flux of antideuterons from hadronic annihilations of dark matter for various Standard Model final states and ...
A Barrau, A Barrau, A Birkedal, A Bottino, A Ibarra, A Kurylov, A Menon, AW Graham, AW Strong, C Arina, CB Braeuninger, CB Jackson, CP Burgess, D Maurin, D Tucker-Smith, DP Finkbeiner, E Aprile, E Nezri, E Ponton, EA Baltz, F Donato, F Donato, F Donato, F Donato, F Donato, F Halzen, G Jungman, G Kane, G Servant, G Servant, H Baer, H Baer, H Baer, H Baer, H Baer, H Baer, H Baer, H Fuke, H Fuke, H-C Cheng, HC Cheng, J Hisano, J Hubisz, J McDonald, JF Navarro, JN Bahcall, John D. Mason, JW Bieber, K Agashe, K Agashe, K Mori, Lisa Randall, LJ Gleeson, M Beltrán, M Cirelli, M Cirelli, M Kadastik, M Nagai, M Srednicki, N Arkani-Hamed, N Arkani-Hamed, O Adriani, P Chardonnet, P Gondolo, P Grajek, Q-H Cao, R Duperray, S Haino, S Orito, S Schael, S Weinberg, SP Ahlen, T Cohen, T Maeno, T Mitsui, T Moroi, T Sjöstrand, VL Ginzburg, Y Asaoka, Y Cui, Yanou Cui, YM Antipov, Z Ahmed   +82 more
core   +1 more source