Results 71 to 80 of about 319,252 (292)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
On Moderate Deviation Theory in Estimation
The Annals of Statistics, 1983 The performance of a sequence of estimators $\{T_n\}$ of $\theta$ can be measured by the probability concentration of the estimator in an $\varepsilon_n$-neighborhood of $\theta$. Classical choices of $\varepsilon_n$ are $\varepsilon_n = cn^{-1/2}$ (contiguous case) and $\varepsilon_n = \varepsilon$ fixed for all $n$ (non-local case).
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Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Probabilities of Moderate Deviations in a Banach Space [PDF]
Proceedings of the American Mathematical Society, 1981 (1) P[ S,1Vn/ > tn ] 1 (D(tn) = of -tn) P[ Snl / 0. In this case, called "moderate deviations" by them, they proved that (1) holds without existence of a moment generating function; it suffices that E?XiK2+c+S 0. Also in this case they proved that EIXjIP < oo, Vp < 2 + c, is a necessary condition for (1).
Deo, Chandrakant M., Babu, Gutti Jogesh
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Moderate deviations for functional U-processes [PDF]
Annales de l'Institut Henri Poincare (B) Probability and Statistics, 2001 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Moderate Deviations for the Determinant of Wigner Matrices [PDF]
, 2013 We establish a moderate deviations principle (MDP) for the log-determinant $\log | \det (M_n) |$ of a Wigner matrix $M_n$ matching four moments with either the GUE or GOE ensemble. Further we establish Cramér--type moderate deviations and Berry-Esseen bounds for the log-determinant for the GUE and GOE ensembles as well as for non-symmetric and non ...
Döring, Hanna, Eichelsbacher, Peter
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Definition of the border between the far and near field zone for printed antenna arrays with high side lobe suppression [PDF]
Serbian Journal of Electrical Engineering, 2013 The paper defines the border between the far and near field zone of printed antenna arrays. The conventional definition has a limited application in side lobe suppression measurements, especially in the case of high side lobe suppression.
Milijić Marija +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source