Results 31 to 40 of about 42,970 (168)

The Pharmacokinetics, Bioavailability, and Excretion Studies of α-Cyperone in Rats by UHPLC-QQQ-MS/MS

Molecules
α-Cyperone (C15H22O), a critical bioactive sesquiterpene, serves as a representative chemical compound of Cyperi Rhizoma—a classical functional food. To investigate the pharmacokinetic characteristics of α-cyperone, a quantified method was developed in ...
Ye Shang, Yameng Zhu, Kaili Zhang, Zijing Zhang, Huining Geng, Xueyu Liu, Wenwen Li, Lu Chen, Caixia Li, Yang Liu, Huizi Ouyang, Jun He   +11 more
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Lacidophilin tablets relieve irritable bowel syndrome in rats by regulating gut microbiota dysbiosis and intestinal inflammation

Scientific Reports
Irritable bowel syndrome (IBS) is a common clinical functional gastrointestinal disease. It has a complex pathophysiological mechanism, in which the imbalance of gut microbiota might play an important role.
Huiqun Fan, Yang Zhan, Xiaoying Cheng, Mintao Tan, Yingmeng Li, Yanxia Xiong, Qiong Li, Wenjun Liu   +7 more
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Porcine Erythrocyte–PRRSV Interactions: Implications for Targeted Nanodrug Delivery

Veterinary Sciences
Objective: To establish a porcine complement receptor type 1-like (CR1-like)-mediated targeted anti-porcine reproductive and respiratory syndrome virus (PRRSV) nanodrug delivery system by investigating interactions between erythrocytes from Landrace ...
Wei Yin, Jingze Li, Haoxiang Yao, Jingyi Qiao, Jia Zhong, Yaogui Sun, Hongquan Li, Kuohai Fan, Zhenbiao Zhang, Na Sun, Panpan Sun, Huizhen Yang, Jianzhong Wang   +12 more
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Parvoviruses NS1 oncolytic attributes: mechanistic insights and synergistic anti-tumor therapeutic strategies

Frontiers in Microbiology
Parvovirus is comprised of a single-stranded DNA structure, encompassing distinct structural and non-structural proteins. Structural proteins are referred as viral proteins, which facilitate for the viral capsid. Among non-structural proteins, NS1 is the
Abdul Haseeb, Wafa Yousaf, Zhigang Cao, Kuohai Fan, Kuohai Fan, Na Sun, Panpan Sun, Yaogui Sun, Huizhen Yang, Wei Yin, Hua Zhang, Zhenbiao Zhang, Jia Zhong, Jianzhong Wang, Hongquan Li   +14 more
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Structural and Functional Analysis of Porcine CR1-like Proteins in C4b-Mediated Immune Responses

Veterinary Sciences
The complement system is crucial for immune defense, linking innate and adaptive immunity. In the classical and lectin pathways, C4 is split into C4b, triggering opsonization, lysis, and the removal of pathogens and damaged cells. Dysregulated activation
Wei Yin, Nan Wang, Jingze Li, Haoxiang Yao, Qiongyu Li, Hongquan Li, Kuohai Fan, Jia Zhong, Zhenbiao Zhang, Na Sun, Panpan Sun, Huizhen Yang, Jianzhong Wang, Yaogui Sun   +13 more
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Pharmacokinetic Profile of Matrine in Pigs Following Intravenous and Oral Administration

Veterinary Sciences
The search for effective alternatives or adjuncts to conventional anti-infective strategies in food animals has increased interest in plant-derived bioactive compounds.
Jianzhong Wang, Hang Yan, Jing Liu, Rui Zhou, Wei Yin, Jia Zhong, Panpan Sun, Na Sun, Zhenbiao Zhang, Yaogui Sun, Huizhen Yang, Kuohai Fan, Hongquan Li   +12 more
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Modern Architecture and Modern Furniture

Docomomo Journal, 2012
Modern architecture and Modern furniture originated almost during the same period of time. Modern architects needed furniture compatible with their architecture and because it was not available on the market, architects had to design it themselves. This does not only apply for the period between 1920 and 1940, as other ambitious architectures had tried
openaire   +3 more sources

Postbiotic from Lactobacillus acidophilus Inhibits Ferroptosis in Intestinal Stem Cells via Microbiota–AhR Axis to Mitigate Colitis

Food Frontiers
Inflammatory bowel disease (IBD) is a chronic, progressive intestinal disorder. Dysbiosis of the gut microbiota is strongly implicated in the onset and progression of IBD. Microbiome‐based interventions offer promising therapeutic potential. Lacidophilin
Denglong Sun, Chenxuan Wang, Qigui Fan, Yang Zhan, Xiaoying Cheng, Jingwen Zhang, Qinxin Wang, Yingmeng Li, Qiong Li, Yanxia Xiong, Wenjun Liu   +10 more
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Analysis of the anti-PCV2 mechanism of Lactobacillus acidophilus based on non-target metabolomics and high-throughput molecular docking

Frontiers in Microbiology
Our previous studies have revealed that L. acidophilus possesses inhibitory effects on PCV2 proliferation in vivo, although the underlying mechanisms remain elusive. Probiotics like L.
Zhigang Cao, Xiaoya Ling, Abdul Haseeb, Panpan Sun, Hua Zhang, Wei Yin, Kuohai Fan, Huizhen Yang, Zhenbiao Zhang, Jia Zhong, Yaogui Sun, Na Sun, Hongquan Li   +12 more
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Pharmacology-Driven Dissection of Core Component Sets of Xuefu Zhuyu Decoction in Blood Stasis-Related Cardiovascular Diseases

Pharmaceuticals
Endothelial dysfunction, chronic inflammation, immune dysregulation, oxidative stress, mitochondrial dysfunction, and metabolic disturbances collectively contribute to cardiovascular diseases (CVDs) associated with blood stasis patterns.
Xuyang Dai, Dongsheng Ba, Miansheng Gao, Chen Liang, Ximeng Zhang, Huijuan Yu, Xin Chai, Yuefei Wang   +7 more
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