Results 91 to 100 of about 3,734,352 (281)
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Praetorius Versus Zarlino: The Question of Modes
This article deals with the question of modes as it is discussed in Gioseffo Zarlino’s Istitutioni harmoniche and Michael Praetorius’s Syntagma musicum.
Nejc Sukljan
doaj +1 more source
We address the nonadiabatic quantum dynamics of macrosystems with several coupled electronic states, taking into account the possibility of multi-state conical intersections.
Cederbaum, Lorenz S. +1 more
core +2 more sources
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Nonlinear modes in the harmonic PT-symmetric potential
We study the families of nonlinear modes described by the nonlinear Schr\"odinger equation with the PT-symmetric harmonic potential $x^2-2i\alpha x$. The found nonlinear modes display a number of interesting features. In particular, we have observed that
Dmitry A. Zezyulin +4 more
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Coupled phonon-ripplon modes in a single wire of electrons on the liquid-helium surface
The coupled phonon-ripplon modes of the quasi-one-dimensional electron chain on the liquid helium sutface are studied. It is shown that the electron-ripplon coupling leads to the splitting of the collective modes of the wire with the appearance of low ...
A. M. C. Valkering +22 more
core +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Predictive Control of Three Phase Inverter for Different Conduction Modes with Filter
Three-phase inverters are commonly employed in higher power industrial applications like UPS, control of various motor, wind power conversion system as well as in different industrial processes.
Muhammad Ishtiaq Zahoor +5 more
doaj

