Results 101 to 110 of about 2,063,794 (297)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

A novel method for integrating chromatographic fingerprint analytical units of Chinese materia medica: the matching frequency statistical moment method

Digital Chinese Medicine
Objective: To facilitate the quality evaluation suitable for the unique characteristics of Chinese materia medica (CMM) by developing and implementing a novel approach known as the matching frequency statistical moment (MFSM) method.
Haiying Li, Xue Pan, Mincun Wang, Wenjiao Li, Peng He, Sheng Huang, Fuyuan He   +6 more
doaj   +1 more source

A Generic Checkpoint-Restart Mechanism for Virtual Machines [PDF]

, 2012
It is common today to deploy complex software inside a virtual machine (VM). Snapshots provide rapid deployment, migration between hosts, dependability (fault tolerance), and security (insulating a guest VM from the host).
Cooperman, Gene, Garg, Rohan, Sodha, Komal   +2 more
core  

Holographic Description of Gravitational Anomalies

, 2006
The holographic duality can be extended to include quantum theories with broken coordinate invariance leading to the appearance of the gravitational anomalies.
A. Garcia, A. Karch, A.R. Gover, C. Fefferman, C. Imbimbo, C.R. Graham, D. Freed, E. Witten, F. Bastianelli, G. 't Hooft, H. Leutwyler, I. Papadimitriou, I. Papadimitriou, J. de Boer, J.A. Harvey, J.A. Harvey, J.M. Maldacena, M. Bañados, M. Bañados, M. Bianchi, M. Henningson, M.B. Green, M.T. Anderson, P. Kraus, P. Kraus, R. Gerlach, S.N. Solodukhin, S.W. Hawking   +27 more
core   +4 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Allergens from wheat and wheat products: A comprehensive review on allergy mechanisms and modifications

Food Chemistry: X
Wheat is one of major human staple foods, contributing an important source of dietary protein. However, some people are allergic to wheat-based foods.
Nan Jiang, Yu Wang, Yasai Sun, Zhe Gao, Dongcheng Liu, Bimal Chitrakar   +5 more
doaj   +1 more source

Interplay Between Different Epigenetic Modifications and Mechanisms

, 2010
Cellular functions including transcription regulation, DNA repair, and DNA replication need to be tightly regulated. DNA sequence can contribute to the regulation of these mechanisms. This is exemplified by the consensus sequences that allow the binding of specific transcription factors, thus regulating transcription rates.
openaire   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

A Modification of Nambu's Mechanics

, 1997
revised version, 10 pages AMS ...
openaire   +2 more sources