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Current Opinion in Lipidology, 1994
Oxidatively damaged LDL may be of pivotal importance in atherogenesis. This review focuses on the cellular pathways involved in LDL oxidation in vitro, the biological properties of oxidized LDL, and the implications of these findings for the role of LDL oxidation in the development of atherosclerosis.
A, Chait, J W, Heinecke
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Oxidatively damaged LDL may be of pivotal importance in atherogenesis. This review focuses on the cellular pathways involved in LDL oxidation in vitro, the biological properties of oxidized LDL, and the implications of these findings for the role of LDL oxidation in the development of atherosclerosis.
A, Chait, J W, Heinecke
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RNA Modifications: Reversal Mechanisms and Cancer
Biochemistry, 2018An emerging molecular understanding of RNA alkylation and its removal is transforming our knowledge of RNA biology and its interplay with cancer chemotherapy responses. DNA modifications are known to perform critical functions depending on the genome template, including gene expression, DNA replication timing, and DNA damage protection, yet current ...
Roopa Thapar +6 more
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Posttranslational modifications in diabetes: Mechanisms and functions
Reviews in Endocrine and Metabolic Disorders, 2022As one of the most widespread chronic diseases, diabetes and its accompanying complications affect approximately one tenth of individuals worldwide and represent a growing cause of morbidity and mortality. Accumulating evidence has proven that the process of diabetes is complex and interactive, involving various cellular responses and signaling ...
Ang Hu +3 more
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Surface modifications for mechanical applications
Hyperfine Interactions, 1994Chemical and high energy beam conversion coatings, as well as PVD thin films, are characterised to correlate microstructures and mechanical properties. In particular, thermochemical boriding and laser surface melting are considered to produce conversion coatings on iron alloys, and physical vapour techniques to deposit thin films of titanium nitride on
M. Carbucicchio, G. Palombarini
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Mechanisms of DNA methylation and histone modifications
2023The field of genetics has expanded a lot in the past few decades due to the accessibility of human genome sequences, but still, the regulation of transcription cannot be explicated exclusively by the sequence of DNA of an individual. The coordination and crosstalk between chromatin factors which are conserved is indispensable for all living creatures ...
Santoshi, Acharjee +3 more
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Modification of spastic gait through mechanical damping
Journal of Biomechanics, 1985The effect of dissipative mechanical loads on spastic gait has been studied, to evaluate the feasibility of using mechanically damped orthoses to effect functional improvements in the gait of spastic patients. This concept is based on a hypothesis citing uninhibited, velocity-dependent stretch reflexes as a possible causal factor in spastic gait ...
B E, Maki, M J, Rosen, S R, Simon
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