Results 91 to 100 of about 101,065 (307)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

MODIFIED ATMOSPHERE PACKAGING OF GRAPES [PDF]

HortScience, 1992
Grapes (Vitis vinifera L. cv. Thompson Seedless) were packed in low density (LDPE) and high density (HDPE) polyethylene bags (Bag size: 25×25 cm containing 300 g of fruit). LDPE and HDPE films had a thickness of 38.7 and 28.2 μm, water permeability of 960 and 720 g/m2.hr.atm., and O2 permeability of 7030 and 3700 cc/m2.day.atm., respectively.
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Mixture design for food packaging in a modified atmosphere

Agricultural Economics (AGRICECON), 2015
In the past, food packaging was primarily used to support product sales and protect food from contamination or environmental effects which would reduce the life of the food. According to the World Health Organization (WHO), in the United States, from 6.5
Jan HRON, Tomas MACAK
doaj   +1 more source

Development of shelf-life kinetic model for modified atmosphere packaging of fresh sliced mushrooms [PDF]

, 2012
Mushrooms are highly perishable and their shelf-life depends on processing, package properties and environmental conditions during storage and distribution. The aims of this work were to evaluate the effect of temperature and number of film perforations
Mahajan, P. V., Oliveira, Felisbela Maria Araújo, Sousa-Gallagher, M. J., Teixeira, J. A.   +3 more
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Storage of soybean seeds: Packaging and modified atmosphere technology [PDF]

Revista Brasileira de Engenharia Agrícola e Ambiental
The characteristics of materials used in packages for seed storage may have a negative influence in the deterioration process, causing future problems during the period of storage and in emergence in the field.
André F. Capilheira, Jerffeson A. Cavalcante, Gizele I. Gadotti, Bruna R. Bezerra, Nander F. Hornke, Francisco A. Villela   +5 more
doaj   +2 more sources

Development and application of rice starch based edible coating to improve the postharvest storage potential and quality of plum fruit (Prunus salicina) [PDF]

, 2018
The study investigated the possibility of enhancing the shelf life of plum fruit coated with rice starch-ι-carrageenan (RS-ι-car) composite coating blended with sucrose fatty acid esters (FAEs). Film solution (starch 3%, carrageenan 1.5% and FAEs 2%) was
Bowyer, M., Golding, J. B., Pristijono, P., Scarlett, C. J., Singh, S. P., Stathopoulos, Costas E., Thakur, R., Vuong, Q.V.   +7 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Modified Atmosphere Packaging Improves Surface Color of Dark-Cutting Beef

Meat and Muscle Biology, 2018
The objective was to determine the effects of modified atmosphere packaging (MAP) on the surface color of dark-cutting beef that had been aged for 21 d. The USDA Choice (normal-pH; IMPS #180) strip loins ( = 10) and no-roll dark-cutter strip loins ( = 10)
R. M.Mitacek, A. R.English, G. G.Mafi, D. L.VanOverbeke, R.Ramanathan   +4 more
doaj   +1 more source