Results 91 to 100 of about 13,027,602 (171)

Genomic Insights Into Spatiotemporal Dynamics of Acquired Azithromycin Resistance Genes in Salmonella Strains Worldwide

Food Safety and Health, Volume 4, Issue 4, Page 939-948, October 2026.
ABSTRACT Azithromycin has been used for clinical invasive infections caused by fluoroquinolone‐ and third‐generation cephalosporin‐resistant Salmonella, and mass drug administration with azithromycin has been used to reduce under‐5 mortality in children in some countries.
Yuhang Pei, Mengqi Qu, Ziru Yang, Xuebin Xu, Yanan Wang   +4 more
wiley   +1 more source

ST37 Klebsiella pneumoniae: development of carbapenem resistance in vivo during antimicrobial therapy in neonates

, 2017
Aim: To investigate the mechanism leading to in vivo carbapenem resistance development in Klebsiella pneumoniae. Methods: Carbapenemase was detected using the modified carbapenem inactivation method.
Fang Chen, Wei Cao, Pengling Li, Xiaomeng Xia, Min Yang, Jingjing Tian, Kan Zhang, Aiguo Tang, Rong Zheng, Feihu Hu, Min Wang, Xianping Li, Yixin Xie   +12 more
core   +1 more source

Detection of hypervirulence genes in carbapenem resistant Klebsiella pneumoniae from cancer patients at a tertiary referral hospital in Nepal

BMC Infectious Diseases
Background Carbapenem-resistant Klebsiella pneumoniae (CRKP) are a serious public health threat and is linked to high mortality, particularly in immunocompromised and critically ill patients. In addition, hyper-virulent K.
Archana Katuwal Chhetri, Hari Prasad Dhakal, Banita Gurung, Sanjib Adhikari, Supriya Sharma, Megha Raj Banjara, Komal Raj Rijal, Prakash Ghimire   +7 more
doaj   +1 more source

confirmation by modified carbapenem inactivation method.

Indian Journal of Medical Microbiology, 2021
P. Priya, V. DILLIRANI, P. PONNAMMAL
openaire   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

Detection of carbapenemase production in Enterobacterales by mCIM and eCIM: a tertiary care hospital study

Iranian Journal of Microbiology
Background and Objectives: Carbapenem-resistant Enterobacterales (CRE) pose a major healthcare challenge due to high resistance rates and limited treatment options.
Touseefa Shafi, Anjum Ara Mir, Shagufta Roohi, Bashir Fomda, Sanam Rasool Wani, Tufail Ahmed, Samiah Yousuf   +6 more
doaj   +1 more source

Alveolar Macrophages: Development, Respiratory Homeostasis, Signal Pathways, Diseases, and Therapeutic Opportunities

MedComm, Volume 7, Issue 10, October 2026.
Alveolar macrophages: development, respiratory homeostasis, signal pathways, diseases, and therapeutic opportunities: During embryonic development, fetal progenitors migrate to the developing lungs via a CX3CR1‐dependent mechanism to establish the TrAM pool.
Sihan Yang, Ruomeng Li, Chuanjiang Yu, Jing Li, Xikun Zhou   +4 more
wiley   +1 more source

Conserved Asp233–Asp246 hydrogen bond modulates active site dynamics in class A β‐lactamases

Protein Science, Volume 35, Issue 10, October 2026.
Abstract Rigid enzymes catalyze chemical reactions by stabilizing the transition state through a specific conformation. Catalytic residues are precisely positioned, and enzyme dynamics are kept to a minimum. It is thought that conserved residues around the active site (second‐shell residues) play a crucial role in positioning catalytic residues. Asp233
Cristina V. Lopez‐Gallego, Monika Timmer, Jocelyne Vreede, Marcellus Ubbink   +3 more
wiley   +1 more source

Molecular characterization of bla NDM and other carbapenemases genes among carbapenem-resistant Enterobacterales from community-and hospital- acquired urinary tract infections

BMC Infectious Diseases
Introduction Extended Spectrum β-lactamase (ESBLs) and/or carbapenemases producing Enterobacterales present a significant challenge in treating urinary tract infections (UTIs).
Lubna Razaq, Fakhur Uddin, Wissal Audah Alhilfi, Mohammed Alorabi, Muhammad Sohail   +4 more
doaj   +1 more source

Prevalence of Carbapenamase Resistant Kebseilla Pneumoniae and Escherichia Coli by Modified Carbapenem Inactivation Method in a Tertiary Care Hospital of North India.

, 2023
AbstractBackground: Carbapenems are the last resort of antibiotics used in an infection caused by multidrug-resistantEnterobacteriaceae, but current increase in the prevalence of carbapenemase producing Enterobacteriaceae posea clinical challenge.
Shubhdeep Kaur, Harsh Yadav, Shailesh Kawale3, Arun Rajawat   +3 more
openaire   +2 more sources