Results 81 to 90 of about 13,027,602 (171)

Carbapenem-resistant genes primer sets.

, 2023
BackgroundCarbapenem-resistant Enterobacteriaceae (CRE) and Extended-spectrum beta-lactamase (ESBL) production among Gram-negative Enterobacteriaceae is an increasing global challenge due to the high morbidity and mortality associated with their ...
Frank Twum Aboagye (17304867), Alex Owusu-Ofori (5931680), Isaac Owusu-Frimpong (11047490), James Sampah (17304864)   +3 more
core   +1 more source

Stimuli‐Responsive Lipid‐Based Nanocarriers for Antimicrobial Therapy

Advanced Therapeutics, Volume 9, Issue 11, November 2026.
This manuscript demonstrated, through a scoping review of the literature, that modifying lipid nanocarriers with organic and inorganic excipients is a promising alternative to increase in vitro drug release of antimicrobial compounds under the studied stimulus and significantly enhance in vitro and in vivo antimicrobial activity compared to isolated ...
Brenda Maria Silva Bezerra, Adrian Lima Roberto, Luiz Gustavo Girão Lima, Mariana Rillo Sato, Leila Aparecida Chiavacci, João Augusto Oshiro‐Junior   +5 more
wiley   +1 more source

Bacterial Agents and Their Multidrug‐Resistance Profile Among Patients Suspected of Bacterial Infections in Hakim Gizaw Hospital, Debre Berhan, Ethiopia: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 11, November 2026.
ABSTRACT Background and Aims Antimicrobial resistance is a global threat. Bacteria showed higher resistance in Ethiopia, and up‐to‐date data on it is urgently required for effective interventions. This study aimed to determine occurrence of multi‐drug‐resistant (MDR) bacterial isolates among patients presented to Hakim Gizaw Hospital (HGH).
Tizazu Zenebe Zelelie, Ermias Endewunetu, Yosef Temesgen, Demissew Shenkute Gebreyes, Zenawork Sahile, Biniam Mekonnen, Getachew Bizuneh, Asrat Berihun, Berhanu Yitayew   +8 more
wiley   +1 more source

Kesesuaian Fenotipik Menggunakan Simplified Carbapenemase Inactivation Method Dan Genotipik Karbapenemase Pada Isolat Acinetobacter Baumannii Resisten Karbapenem [PDF]

, 2020
Latar belakang Resistensi bakteri terhadap antibiotik menjadi isu kesehatan global diseluruh dunia. Munculnya Carbapenem Resistant Acinetobacter baumanni (CRAB) menjadi isu penting di seluruh dunia.
Cherry Siregar
core  

Phenotypic/Genotypic Profile of Oxa-10-like-Harboring, Carbapenem-Resistant \u3cem\u3ePseudomonas aeruginosa: \u3c/em\u3eUsing Validated Pharmacokinetic/Pharmacodynamic \u3cem\u3ein Vivo \u3c/em\u3eModels to Further Evaluate Enzyme Functionality and Clinical Implications [PDF]

, 2021
In vitro MICs and in vivo pharmacodynamics of ceftazidime and cefepime human-simulated regimens (HSR) against modified carbapenem inactivation method (mCIM)-positive Pseudomonas aeruginosa isolates harboring different OXA-10-like subtypes were described.
Opperman, Christoffel Johannes, Tickler, Isabella A., Pournaras, Spyros, Tenover, Fred C., Gill, Christian M., Vourli, Sophia, Brink, Adrian, Moodley, Clinton, Tootla, Hafsah Deepa, Chu, Chun Yat, Coetzee, Jennifer, Nicolau, David P., Dimopoulos, George   +12 more
core   +1 more source

Antimicrobial Resistance in Periodontal Disease: Rethinking Adjunctive Therapy in the Metagenomics Era, the Pressing Need for Precision Treatment and Periodontal Resistome Mapping

Journal of Cellular and Molecular Medicine, Volume 30, Issue 21, November 2026.
ABSTRACT Systemic antibiotics are effective when used as adjunctive therapy in the treatment of periodontitis; however, their use must be balanced against antimicrobial resistance, which is a major threat to global public health. This review provides an expert synthesis of the literature and a field‐level overview of antimicrobial resistance in ...
Meera Alghafri, Lindsey Edwards, David Moyes, Luigi Nibali   +3 more
wiley   +1 more source

Evaluation of blaOXA-48-like point mutation carbapenemase-producing Enterobacterales in Prapokklao Hospital, Thailand

Microbiology Spectrum
Carbapenemase-producing Enterobacterales (CPE) isolates increasingly carry oxacillinase-48 (OXA-48)-like enzymes encoded by blaOXA-48-like, which can confer high levels of carbapenem resistance.
Sirijan Santajit, Witawat Tunyong, Thida Kong-Ngoen, Weewan Arsheewa, Woranich Hinthong, Pornpan Pumirat, Nitat Sookrung, Nitaya Indrawattana   +7 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, Volume 600, Issue 19, Page 2947-2960, October 2026.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Comparative Evaluation of Four Phenotypic Methods for Detection of Class A and B Carbapenemase-Producing Enterobacteriaceae in China

, 2018
The objective of this study was to evaluate the performance of four phenotypic methods in the detection of carbapenemase-producing Enterobacteriaceae (CPE) in China.
Shuying Yu, Menglan Zhou, Ying-Chun Xu, Qiwen Yang, Danchen Wang, Timothy Kudinha   +5 more
core   +1 more source

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

Advanced Science, Volume 13, Issue 60, 28 October 2026.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie, Zheyu Zhang, Hao Zhang, Linke Bian, Penglong Zheng, Sijia Zhou, Minqi Wang, Mingyu Qu, Yufei Wang, Xinhua Qu, Bing Yue   +10 more
wiley   +1 more source