Results 131 to 140 of about 1,839,177 (303)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Sequence Analysis of Novel Genes in Clinical and Environmental Pseudomonas aeruginosa Iraqi Isolates

open access: yesJournal of Pure and Applied Microbiology, 2018
Study the sequencing of phzM and phzS genes and the effect of their mutation on phenazine production. Pseudomonas aeruginosa has the ability to adapt and grow in a variety of environments and is owing to its wide genetic flexibility.
Huda Hadi Al-Hasnawy
doaj   +1 more source

Electronically tuned optical filters [PDF]

open access: yes
Electro-optical effect of light modifying type for electronically controlling ...
Castellano, J. P.   +3 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

From biological neural networks to thinking machines: Transitioning biological organizational principles to computer technology [PDF]

open access: yes
The three-dimensional organization of the vestibular macula is under study by computer assisted reconstruction and simulation methods as a model for more complex neural systems.
Ross, Muriel D.
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Modifying an ill-fitting simple face mask

open access: yesPediatrics and Neonatology, 2023
Abhishek Bharadwaj, Sandeep Gade
doaj   +1 more source

What works in primary schools? [PDF]

open access: yes
Olmo Silva reviews the evidence on the effectiveness of increasing resources, modifying teaching methods and introducing choice and competition. Policies to improve primary education can involve increasing the resources available to schools, modifying ...
Olmo Silva
core  

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