Results 51 to 60 of about 894,676 (256)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Deoxidation impact on the impurity index of heat resistant steel 40H15N7G7F2MS
Metalurgija, 2017 Analyzing failure causes of the parts made of heat resistant steel shows that one of the defining factors impacting the properties is concentration of harmful impurities both dissolved in steel and being in the form of nonmetallic inclusions. The latter,
A. Z. Issagulov +4 more
doaj
Modifying Orthogonal Drawings for Label Placement
Algorithms, 2016 In this paper, we investigate how one can modify an orthogonal graph drawing to accommodate the placement of overlap-free labels with the minimum cost (i.e., minimum increase of the area and preservation of the quality of the drawing).
Konstantinos G. Kakoulis +1 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Modifying ePADD for Entity Extraction in Non-English Languages [Presentation] [PDF]
Presentation sharing recent advancements in enhancing ePADD, an open-source email archiving tool, by modifying its lexical search and entity extraction pipeline to accommodate a non-English language.
Enstad, Tita, Beauguitte, Pierre
core
NANOSTRUCTURAL PROCESSES OF MELTING, CRYSTALLIZATION AND MODIFYINGS OF METALS
Литьë и металлургия, 2015 It is shown that melting, crystallization and modifying of metals are difficult nanostructural processes. The nanocrystals and atoms of metals, the centers of crystallization of dendrites, surface-active elements, gases modifying elements, poorly soluble
V. Yu. Stetsenko
doaj
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source