Results 61 to 70 of about 611,546 (266)

CRISPR: modifying the life science landscape

open access: yesBioTechniques, 2016
From lampreys to human stem cells, the CRISPR/Cas9 system is challenging our notions of what is possible with genome editing. Nathan Blow talks to researchers pushing the boundaries of CRISPR/Cas9 technology to expand our understanding of biology.
Nathan Blow
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

beta-1,3-glucan modifying enzymes in Aspergillus fumigatus

open access: yesFrontiers in Microbiology, 2013
In Aspergillus fumigatus like in other filamentous ascomycetes, beta-1,3-glucan constitutes a prominent cell wall component being responsible for rigidity of the cell wall structure. In filamentous fungi, softening of the cell wall is absolutely required
Isabelle eMouyna   +2 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Modifying Hebbian Network for Text Cipher

open access: yesمجلة بغداد للعلوم, 2011
The objective of this work is to design and implement a cryptography system that enables the sender to send message through any channel (even if this channel is insecure) and the receiver to decrypt the received message without allowing any intruder to ...
Baghdad Science Journal
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

NANOSTRUCTURAL PROCESSES OF MELTING AND MOULDING OF THE EUTECTIC SILUMIN

open access: yesЛитьë и металлургия, 2016
It is shown that melting and molding of the eutectic silumin are difficult physical and chemical nanostructural processes. In them the major role is played by the centers of crystallization of the eutectic dendrites of aluminum, aluminum nanocrystals ...
V. Yu. Stetsenko
doaj  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

MODIFIED TETANUS. [PDF]

open access: yesThe Lancet, 1917
n ...
openaire   +2 more sources

MAIN PROBLEMS OF MOULDING OF SILUMINS. WAYS OF SOLUTION

open access: yesЛитьë и металлургия, 2016
The main problems of silumin’ moulding are connected with insufficient modifying of casting structure, their considerable inclination to gas porosity, difficult to remove nonmetallic inclusions and these features are shown in the article.
E. I. Marukovich, V. Yu. Stetsenko
doaj  

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