Results 61 to 70 of about 613,285 (267)
CRISPR: modifying the life science landscape
BioTechniques, 2016 From lampreys to human stem cells, the CRISPR/Cas9 system is challenging our notions of what is possible with genome editing. Nathan Blow talks to researchers pushing the boundaries of CRISPR/Cas9 technology to expand our understanding of biology.
Nathan Blow
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
beta-1,3-glucan modifying enzymes in Aspergillus fumigatus
Frontiers in Microbiology, 2013 In Aspergillus fumigatus like in other filamentous ascomycetes, beta-1,3-glucan constitutes a prominent cell wall component being responsible for rigidity of the cell wall structure. In filamentous fungi, softening of the cell wall is absolutely required
Isabelle eMouyna +2 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Modifying Hebbian Network for Text Cipher
مجلة بغداد للعلوم, 2011 The objective of this work is to design and implement a cryptography system that enables the sender to send message through any channel (even if this channel is insecure) and the receiver to decrypt the received message without allowing any intruder to ...
Baghdad Science Journal
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
NANOSTRUCTURAL PROCESSES OF MELTING AND MOULDING OF THE EUTECTIC SILUMIN
Литьë и металлургия, 2016 It is shown that melting and molding of the eutectic silumin are difficult physical and chemical nanostructural processes. In them the major role is played by the centers of crystallization of the eutectic dendrites of aluminum, aluminum nanocrystals ...
V. Yu. Stetsenko
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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MAIN PROBLEMS OF MOULDING OF SILUMINS. WAYS OF SOLUTION
Литьë и металлургия, 2016 The main problems of silumin’ moulding are connected with insufficient modifying of casting structure, their considerable inclination to gas porosity, difficult to remove nonmetallic inclusions and these features are shown in the article.
E. I. Marukovich, V. Yu. Stetsenko
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Revisiting the modifying environment approach
Scottish Journal of Residential Child Care, 2010 Theory is a fundamental piece of professional child and youth care practice, and finding useful, life-space applicable theory that addresses the complex issues presented by the young people in child and youth care is a continual challenge.
Jack Phelan
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