Results 81 to 90 of about 1,120,056 (288)
On isomorphisms between Siegel modular threefolds
The Satake compactification of the moduli space of principally polarized abelian surfaces with a level two structure has a degree 8 endomorphism. The aim of this paper is to show that this result can be extended to other modular threefolds.
Perna, Sara
core +1 more source
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Algebraic orbifold conformal field theories
We formulate the unitary rational orbifold conformal field theories in the algebraic quantum field theory framework. Under general conditions, we show that the orbifold of a given unitary rational conformal field theories generates a unitary modular ...
Borcherds, F. Xu
core +3 more sources
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Euler complexes and geometry of modular varieties
There is a mysterious connection between the multiple polylogarithms at N-th roots of unity and modular varieties. In this paper we "explain" it in the simplest case of the double logarithm. We introduce an Euler complex data on modular curves.
Goncharov, A. B.
core +1 more source
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Irreducible vector-valued modular forms of dimension less than six
An algebraic classification is given for spaces of holomorphic vector-valued modular forms of arbitrary real weight and multiplier system, associated to irreducible, T-unitarizable representations of the full modular group, of dimension less than six ...
Marks, Christopher
core
En este trabajo presentamos una moderna introducción a las formas modulares cuyo contexto de desarrollo es principalmente analítico. Esto último lo aprovechamos sobremanera para evidenciar la naturaleza aritmética de las formas modulares, la cual emplearemos para demostrar completamente la conjetura de Bachet y parcialmente la conjetura de Ramanujan.
openaire +3 more sources

