Results 61 to 70 of about 140,029 (306)
CAMAC modular programmable function generator [PDF]
, 1980 A CAMAC modular programmable function generator has been developed. The device contains a 1024 word by 12-bit memory, a 12-bit digital-to-analog converter with a 600 ns settling time, an 18-bit programmable frequency register, and two programmable ...
Hendricks, R.W. +2 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Remark on modular weights in low-energy effective field theory from type II string theory
Journal of High Energy Physics, 2023 We revisit the modular weights in type IIB magnetized D-brane models. The simple analysis of wave function shows that the four-dimensional matter fields have the modular weight -1/2, but it may shift as one in type IIA intersecting D-brane models.
Shota Kikuchi +5 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Non-Abelian T-duality and modular invariance
Nuclear Physics B, 2018 Two-dimensional σ-models corresponding to coset CFTs of the type (gˆk⊕hˆℓ)/hˆk+ℓ admit a zoom-in limit involving sending one of the levels, say ℓ, to infinity.
Benjo Fraser +2 more
doaj +1 more source
Modular equations and distortion functions [PDF]
The Ramanujan Journal, 2007 Modular equations occur in number theory, but it is less known that such equations also occur in the study of deformation properties of quasiconformal mappings. The authors study two important plane quasiconformal distortion functions, obtaining monotonicity and convexity properties, and finding sharp bounds for them.
Anderson, G. D. +2 more
openaire +3 more sources
A Criteria-based Measure of Similarity between Product Functionalities [PDF]
, 2009 Organised by: Cranfield UniversityToday‘s customers request product functions and not components. A specific, modular description of the product functions and how they are realized becomes widely accepted to track how a product function is realized and
Politze, D. P., Dierssen, S.
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Functional Annotation of Hierarchical Modularity
PLoS ONE, 2012 In biological networks of molecular interactions in a cell, network motifs that are biologically relevant are also functionally coherent, or form functional modules. These functionally coherent modules combine in a hierarchical manner into larger, less cohesive subsystems, thus revealing one of the essential design principles of system-level cellular ...
Kanchana Padmanabhan +2 more
openaire +4 more sources