Results 81 to 90 of about 611,660 (282)

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Thermal correlation functions of KdV charges in 2D CFT

Journal of High Energy Physics, 2019
Two dimensional CFTs have an infinite set of commuting conserved charges, known as the quantum KdV charges, built out of the stress tensor. We compute the thermal correlation functions of the these KdV charges on a circle.
Alexander Maloney, Gim Seng Ng, Simon F. Ross, Ioannis Tsiares   +3 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Root- T T ¯ $$ T\overline{T} $$ deformed CFT partition functions at large central charge

Journal of High Energy Physics
In this work, we investigate the partition function of 2d CFT under root- T T ¯ $$ T\overline{T} $$ deformation. We demonstrate that the deformed partition function satisfies a flow equation.
Miao He
doaj   +1 more source

Bilateral series in terms of mixed mock modular forms

Journal of Inequalities and Applications, 2016
The number of strongly unimodal sequences of weight n is denoted by u ∗ ( n ) $u^{*}(n)$ . The generating functions for { u ∗ ( n ) } n = 1 ∞ $\{u^{*}(n)\}_{n=1}^{\infty}$ are U ∗ ( q ) = ∑ n = 1 ∞ u ∗ ( n ) q n $U^{*}(q)=\sum_{n=1}^{\infty}u^{*}(n)q^{n}$
Bin Chen, Haigang Zhou
doaj   +1 more source

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source

Nonlinear Fredholm equations in modular function spaces

Electronic Journal of Differential Equations, 2019
We investigate the existence of solutions in modular function spaces of the Fredholm integral equation $$ \Phi(\theta) = g(\theta) + \int^1_0 f(\theta,\sigma, \Phi(\sigma)) \,d\sigma, $$ where $\Phi(\theta), g(\theta)\in L_{\rho}, \theta\in [0,1 ...
Mostafa Bachar
doaj  

Modular Functional Descriptions

Electronic Notes in Theoretical Computer Science, 2008
AbstractThe construction of reactive systems often requires the combination of different individual functionalities, thus leading to a complex overall behavior. To achieve an efficient construction of reliable systems, a structured approach to the definition of the behavior is needed. Here, functional modularization supports a separation of the overall
openaire   +1 more source