Results 71 to 80 of about 117,034 (264)

Lessons from the Ramond sector

SciPost Physics, 2020
We revisit the consistency of torus partition functions in (1+1)$d$ fermionic conformal field theories, combining traditional ingredients of modular invariance/covariance with a modernized understanding of bosonization/fermionization dualities.
Nathan Benjamin, Ying-Hsuan Lin
doaj   +1 more source

Functional Annotation of Hierarchical Modularity

PLoS ONE, 2012
In biological networks of molecular interactions in a cell, network motifs that are biologically relevant are also functionally coherent, or form functional modules. These functionally coherent modules combine in a hierarchical manner into larger, less cohesive subsystems, thus revealing one of the essential design principles of system-level cellular ...
Kanchana Padmanabhan, Kuangyu Wang, Nagiza F Samatova   +2 more
openaire   +4 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Thermal correlation functions of KdV charges in 2D CFT

Journal of High Energy Physics, 2019
Two dimensional CFTs have an infinite set of commuting conserved charges, known as the quantum KdV charges, built out of the stress tensor. We compute the thermal correlation functions of the these KdV charges on a circle.
Alexander Maloney, Gim Seng Ng, Simon F. Ross, Ioannis Tsiares   +3 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Bilateral series in terms of mixed mock modular forms

Journal of Inequalities and Applications, 2016
The number of strongly unimodal sequences of weight n is denoted by u ∗ ( n ) $u^{*}(n)$ . The generating functions for { u ∗ ( n ) } n = 1 ∞ $\{u^{*}(n)\}_{n=1}^{\infty}$ are U ∗ ( q ) = ∑ n = 1 ∞ u ∗ ( n ) q n $U^{*}(q)=\sum_{n=1}^{\infty}u^{*}(n)q^{n}$
Bin Chen, Haigang Zhou
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Root- T T ¯ $$ T\overline{T} $$ deformed CFT partition functions at large central charge

Journal of High Energy Physics
In this work, we investigate the partition function of 2d CFT under root- T T ¯ $$ T\overline{T} $$ deformation. We demonstrate that the deformed partition function satisfies a flow equation.
Miao He
doaj   +1 more source