Results 71 to 80 of about 608,878 (283)
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Thermal correlation functions of KdV charges in 2D CFT
Journal of High Energy Physics, 2019 Two dimensional CFTs have an infinite set of commuting conserved charges, known as the quantum KdV charges, built out of the stress tensor. We compute the thermal correlation functions of the these KdV charges on a circle.
Alexander Maloney +3 more
doaj +1 more source
Non-cuspidal Hida theory for Siegel modular forms and trivial zeros of $p$-adic $L$-functions
, 2018 We study the derivative of the standard $p$-adic $L$-function associated with a $P$-ordinary Siegel modular form (for $P$ a parabolic subgroup of $\mathrm{GL}(n)$) when it presents a semi-stable trivial zero.
Liu, Zheng, Rosso, Giovanni
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Bilateral series in terms of mixed mock modular forms
Journal of Inequalities and Applications, 2016 The number of strongly unimodal sequences of weight n is denoted by u ∗ ( n ) $u^{*}(n)$ . The generating functions for { u ∗ ( n ) } n = 1 ∞ $\{u^{*}(n)\}_{n=1}^{\infty}$ are U ∗ ( q ) = ∑ n = 1 ∞ u ∗ ( n ) q n $U^{*}(q)=\sum_{n=1}^{\infty}u^{*}(n)q^{n}$
Bin Chen, Haigang Zhou
doaj +1 more source
Effects of modular nursing model for typical issues on enteral nutrition status, immune function, and quality of life in colon cancer patients [PDF]
, 2023 Fengxia Chen +4 more
openalex +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Root- T T ¯ $$ T\overline{T} $$ deformed CFT partition functions at large central charge
Journal of High Energy PhysicsIn this work, we investigate the partition function of 2d CFT under root- T T ¯ $$ T\overline{T} $$ deformation. We demonstrate that the deformed partition function satisfies a flow equation.
Miao He
doaj +1 more source