Results 81 to 90 of about 117,034 (264)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Modular Functional Descriptions

open access: yesElectronic Notes in Theoretical Computer Science, 2008
AbstractThe construction of reactive systems often requires the combination of different individual functionalities, thus leading to a complex overall behavior. To achieve an efficient construction of reliable systems, a structured approach to the definition of the behavior is needed. Here, functional modularization supports a separation of the overall
openaire   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Nonlinear Fredholm equations in modular function spaces

open access: yesElectronic Journal of Differential Equations, 2019
We investigate the existence of solutions in modular function spaces of the Fredholm integral equation $$ \Phi(\theta) = g(\theta) + \int^1_0 f(\theta,\sigma, \Phi(\sigma)) \,d\sigma, $$ where $\Phi(\theta), g(\theta)\in L_{\rho}, \theta\in [0,1 ...
Mostafa Bachar
doaj  

On modular functions in characteristic 𝑝 [PDF]

open access: yesTransactions of the American Mathematical Society, 1978
Let k = F q ( T ) k\, = \,{{\textbf {F}}_q}\left ( T \right ) be a function field of one variable over a finite field
openaire   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Semigroups and Evolution Equations in Modular Function Spaces

open access: yesAxioms
This paper develops the theory of strongly continuous semigroups and abstract evolution equations in modular function spaces. We study the autonomous problem u˙(t)=Bu(t) with initial condition u(0)=u0∈Lρ, where B is the infinitesimal generator of a ...
Mostafa Bachar
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Fixed point theorem and its application to perturbed integral equations in modular function spaces

open access: yesElectronic Journal of Differential Equations, 2005
In this paper, we present a modular version of Krasnoselskii's fixed point theorem. Then this result is applied to the existence of solutions to perturbed integral equations in modular function spaces.
Ahmed Hajji, Elaidi Hanebaly
doaj  

Modularity in Argyres-Douglas theories with a = c

open access: yesJournal of High Energy Physics
We consider a family of Argyres-Douglas theories, which are 4D N $$ \mathcal{N} $$ = 2 strongly coupled superconformal field theories (SCFTs) but share many features with 4D N $$ \mathcal{N} $$ = 4 super-Yang-Mills theories.
Hongliang Jiang
doaj   +1 more source

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