Results 81 to 90 of about 10,760,607 (302)

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

open access: yesFEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić   +3 more
wiley   +1 more source

The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions

open access: yesFEBS Open Bio, EarlyView.
Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh   +2 more
wiley   +1 more source

Nonlinear Fredholm equations in modular function spaces

open access: yesElectronic Journal of Differential Equations, 2019
We investigate the existence of solutions in modular function spaces of the Fredholm integral equation $$ \Phi(\theta) = g(\theta) + \int^1_0 f(\theta,\sigma, \Phi(\sigma)) \,d\sigma, $$ where $\Phi(\theta), g(\theta)\in L_{\rho}, \theta\in [0,1 ...
Mostafa Bachar
doaj  

Teaching Python with team‐based learning: using cloud‐based notebooks for interactive coding education

open access: yesFEBS Open Bio, EarlyView.
This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley   +1 more source

Modularity in Argyres-Douglas theories with a = c

open access: yesJournal of High Energy Physics
We consider a family of Argyres-Douglas theories, which are 4D N $$ \mathcal{N} $$ = 2 strongly coupled superconformal field theories (SCFTs) but share many features with 4D N $$ \mathcal{N} $$ = 4 super-Yang-Mills theories.
Hongliang Jiang
doaj   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

open access: yesFEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu   +6 more
wiley   +1 more source

Fixed point theorem and its application to perturbed integral equations in modular function spaces

open access: yesElectronic Journal of Differential Equations, 2005
In this paper, we present a modular version of Krasnoselskii's fixed point theorem. Then this result is applied to the existence of solutions to perturbed integral equations in modular function spaces.
Ahmed Hajji, Elaidi Hanebaly
doaj  

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