Results 51 to 60 of about 477,721 (333)
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
All-order differential equations for one-loop closed-string integrals and modular graph forms
Journal of High Energy Physics, 2020 We investigate generating functions for the integrals over world-sheet tori appearing in closed-string one-loop amplitudes of bosonic, heterotic and type-II theories.
Jan E. Gerken +2 more
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
The Hierarchical Modular Structure of HER2+ Breast Cancer Network
Frontiers in Physiology, 2018 HER2-enriched breast cancer is a complex disease characterized by the overexpression of the ERBB2 amplicon. While the effects of this genomic aberration on the pathology have been studied, genome-wide deregulation patterns in this subtype of cancer are ...
Sergio Antonio Alcalá-Corona +6 more
doaj +1 more source
To the cusp and back: resurgent analysis for modular graph functions
Journal of High Energy Physics, 2022 Modular graph functions arise in the calculation of the low-energy expansion of closed-string scattering amplitudes. For toroidal world-sheets, they are SL(2, ℤ)-invariant functions of the torus complex structure that have to be integrated over the ...
Daniele Dorigoni +2 more
doaj +1 more source
, 2010 We define two-parameter generalizations of Andrews' $(k+1)$-marked odd Durfee symbols and $2k$th symmetrized odd rank moments, and study the automorphic properties of some of their generating functions.
Andrews +8 more
core +1 more source
DynaMod: dynamic functional modularity analysis [PDF]
Nucleic Acids Research, 2010 A comprehensive analysis of enriched functional categories in differentially expressed genes is important to extract the underlying biological processes of genome-wide expression profiles. Moreover, identification of the network of significant functional modules in these dynamic processes is an interesting challenge.
Sun, CH Sun, Choong-Hyun +3 more
openaire +3 more sources
On values of weakly holomorphic modular functions at divisors of meromorphic modular forms [PDF]
, 2021 Daeyeol Jeon +2 more
openalex +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source