Results 131 to 140 of about 1,844,961 (296)

Dynamic Channel Allocation Techniques Using Adaptive Modulation and Adaptive Antennas

open access: yes, 2001
This contribution studies the impact of adaptive quadrature amplitude modulation (AQAM) on network performance when applied to a cellular network, using adaptive antennas in conjunction with both fixed channel allocation (FCA) and locally distributed ...
Blogh, J.S., Cherriman, P.J., Hanzo, L.
core   +1 more source

A metabolite-pair controlled quiescence switch via ATP-dependent phase separation

open access: yesScientific Reports
Amino acid oxidation during carbon starvation inevitably generates NH₄⁺ and HCO₃⁻ as byproducts. Here we show that this metabolite pair acts synergistically to deplete cellular ATP, a task neither accomplishes alone.
Mengyuan Wang   +3 more
doaj   +1 more source

Adaptive modulation schemes for optical wireless communication systems [PDF]

open access: yes
High-speed wireless optical communication links have become more popular for personal mobile applications. This is a consequence of the increasing demand from the personal information service boom.
Zeng, Yu
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Enhanced fragmentation of water dications upon high Rydberg states

open access: yesNature Communications
The ionization and fragmentation of water are fundamental processes across numerous scientific and technological fields, yet the relaxation pathways of water dications-particularly the rare D+ + O+ + D channel-remain poorly understood.
Jiaqi Zhou   +12 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Understanding attenuated positive facial expression in depressed women: central role of dorsal raphe network alterations and associated serotonin transporter methylation

open access: yesScientific Reports
Anhedonia and loss of pleasure are core features of major depressive disorder, yet their neurobiological basis remains unclear. We examined dynamic facial responses to naturalistic emotional video stimuli in women with major depressive disorder and ...
Changjin Jung   +15 more
doaj   +1 more source

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