Results 111 to 120 of about 2,665,852 (303)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Sirtuin Modulators [PDF]

open access: yes, 2011
Members of the sirtuin family including the founding protein Sir2 in Saccharomyces cerevisiae have been linked to lifespan extension in simple organisms. This finding prompted evaluation of the role of Sir2 orthologues in many aging-associated conditions including neurodegeneration, type II diabetes and cancer.
Sumit S, Mahajan   +3 more
openaire   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Method and apparatus for quadriphase-shift-key and linear phase modulation [PDF]

open access: yes, 1980
A submultiple of an S-band transmitter output frequency was divided equally between a linear phase modulation branch and a QPSK modulation branch. The linear modulation branch includes a multiplier to increase the carrier frequency to a level which, when
Hermesmeyer, C. E.
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

A Metastructure Based on Amorphous Carbon for High Efficiency and Selective Solar Absorption

open access: yesNanomaterials
Efficient solar thermal conversion is crucial for renewable clean energy technologies such as solar thermal power generation, solar thermophotovoltaic and seawater desalination.
Junli Su   +8 more
doaj   +1 more source

Effects of self-phase modulation on weak nonlinear optical quantum gates

open access: yes, 2007
A possible two-qubit gate for optical quantum computing is the parity gate based on the weak Kerr effect. Two photonic qubits modulate the phase of a coherent state, and a quadrature measurement of the coherent state reveals the parity of the two qubits ...
Pieter Kok, R. W. Boyd, S. M. Barnett
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Koszul Modules

open access: yesJournal of Pure and Applied Algebra, 2005
From the authors' introduction: Consider a noetherian local ring \(R\) with maximal ideal \(\mathcal M\) and residue field \(k\). Given a finitely generated \(R\)-module \(M\) and \(F\) its minimal free resolution, denote \(\text{lin}^R(F)\) the associated graded complex of \(F\) arising from the standard \(\mathcal M\)-adic filtration.
Herzog, Jürgen, Iyengar, Srikanth
openaire   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

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