Results 1 to 10 of about 766,195 (336)

Neurocapillary-modulation [PDF]

Brain Stimulation, 2021
We consider two consequences of brain capillary ultrastructure in neuromodulation. First, blood-brain barrier (BBB) polarization as a consequence of current crossing between interstitial space and the blood. Second, interstitial current flow distortion around capillaries impacting neuronal stimulation.We developed computational models of BBB ...
Niranjan Khadka, Marom Bikson
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Compound 275# Induces Mitochondria-Mediated Apoptosis and Autophagy Initiation in Colorectal Cancer Cells through an Accumulation of Intracellular ROS

Molecules, 2023
Colorectal cancer (CRC) is the most common intestinal malignancy, and nearly 70% of patients with this cancer develop metastatic disease. In the present study, we synthesized a novel compound, termed N-(3-(5,7-dimethylbenzo [d]oxazol-2-yl)phenyl)-5 ...
Dong-Lin Yang, Yong Li, Shui-Qing Ma, Ya-Jun Zhang, Jiu-Hong Huang, Liu-Jun He   +5 more
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Inhibition of MORC2 Mediates HDAC4 to Promote Cellular Senescence through p53/p21 Signaling Axis

Molecules, 2022
(1) Background: Colorectal cancer (CRC) is a common gastrointestinal malignancy, accounting for the second largest gastrointestinal tumor. MORC2, a newly discovered chromatin remodeling protein, plays an important role in the biological processes of ...
Kepeng Ou, Youjian Li, Yiling Long, Yafei Luo, Dianyong Tang, Zhongzhu Chen   +5 more
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Demethylzeylasteral (T-96) initiates extrinsic apoptosis against prostate cancer cells by inducing ROS-mediated ER stress and suppressing autophagic flux

Biological Research, 2021
Background Demethylzeylasteral (T-96) is a pharmacologically active triterpenoid monomer extracted from Tripterygium wilfordii Hook F (TWHF) that has been reported to exhibit anti-neoplastic effects against several types of cancer cells.
Dong-lin Yang, Ya-jun Zhang, Liu-jun He, Chun-sheng Hu, Li-xia Gao, Jiu-hong Huang, Yan Tang, Jie Luo, Dian-yong Tang, Zhong-zhu Chen   +9 more
doaj   +1 more source

\(L\)-Modules

Bulletin of the Section of Logic, 2023
In this paper, considering \(L\)-algebras, which include a significant number of other algebraic structures, we present a definition of modules on \(L\)-algebras (\(L\)-modules). Then we provide some examples and obtain some results on \(L\)-modules.
Simin Saidi Goraghani, Rajab Ali Borzooei   +1 more
openaire   +2 more sources

Pyrrolyldihydropyrazino[1,2-a]indoletrione Analogue Microtubule Inhibitor Induces Cell-Cycle Arrest and Apoptosis in Colorectal Cancer Cells

Molecules, 2023
In this study, 2-benzyl-10a-(1H-pyrrol-2-yl)-2,3-dihydropyrazino[1,2-a]indole-1,4,10(10aH)-trione (DHPITO), a previously identified inhibitor against hepatocellular carcinoma cells, is shown to exert its cytotoxic effects by suppressing the proliferation
Dong-Lin Yang, Hong-Xia Qin, Na-Na Zhang, Ya-Jun Zhang, Jiu-Hong Huang, Chun-Sheng Hu, Xiao-Xue Zhang, Yong Li, Liu-Jun He   +8 more
doaj   +1 more source

Memory modulation. [PDF]

Behavioral Neuroscience, 2008
Our memories are not all created equally strong: Some experiences are well remembered while others are remembered poorly, if at all. Research on memory modulation investigates the neurobiological processes and systems that contribute to such differences in the strength of our memories.
Benno, Roozendaal, James L, McGaugh
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Selective sulfonylation and isonitrilation of para-quinone methides employing TosMIC as a source of sulfonyl group or isonitrile group

Beilstein Journal of Organic Chemistry, 2021
Chemoselective sulfonylation and isonitrilation reactions for the divergent synthesis of valuable diarylmethyl sulfones and isonitrile diarylmethanes starting from easy-to-synthesize para-quinone methides (p-QMs) and commercially abundant p ...
Chuanhua Qu, Run Huang, Yong Li, Tong Liu, Yuan Chen, Guiting Song   +5 more
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Compact and Efficient Thin‐Film Lithium Niobate Modulators

Advanced Photonics Research, 2023
Thin‐film lithium niobate (TFLN) modulators have garnered significant attention in the field of integrated photonics due to their ability to manipulate light.
Guanyu Chen, Yuan Gao, Hong-Lin Lin, Aaron J. Danner   +3 more
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Crystal structure of methyl 2-(4-(3-iodopyrazolo[1,5-a]pyrimidin-6-yl)phenyl)acetate, C15H12IN3O2

Zeitschrift für Kristallographie - New Crystal Structures, 2020
C15H12IN3O2, triclinic, P1̄ (no. 2), a = 4.511(2) Å, b = 11.891(6) Å, c = 14.557(7) Å, α = 109.709(9)°, β = 96.971(9)°, γ = 97.054(9)°, V = 718.4(6) Å3, Z = 2, Rgt(F) = 0.0449, wRref(F2) = 0.1052, T = 293(2) K.
Fang Bo, Jiang Fang Fang, Meng Jiang Ping   +2 more
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