Results 31 to 40 of about 2,084 (272)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

MOESM2 of Network modules uncover mechanisms of skeletal muscle dysfunction in COPD patients

open access: yes, 2018
Additional file 2: Table S1. Number of differentially expressed genes in the different groups and conditions. Table S2. Previous measurements: List of variables measured. Table S3. Network modules: HotNet2 results. Table S4.
Susana Kalko (207125)   +9 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Intrinsic chiral microporous polymer membranes by interfacial polymerization for precise enantioseparation

open access: yesAdvanced Membranes
Enantiomers of chiral drugs frequently exhibit distinct pharmacological activities, metabolic pathways, rates of metabolism, and toxicological profiles.
Zichen Li   +4 more
doaj   +1 more source

Unified Differential Spatial Modulation

open access: yesIEEE Wireless Communications Letters, 2014
This letter proposes a unified differential spatial modulation (DSM) architecture, where a flexible rate-diversity tradeoff is achieved, while enabling a simple single-RF transmitter structure along with non-coherent detection that dispenses with channel estimation at the receiver.
Naoki Ishikawa, Shinya Sugiura
openaire   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Differential projective modules over differential rings, II

open access: yesCommunications in Algebra, 2022
Differential modules over a commutative differential ring R which are finitely generated projective as ring modules, with differential homomorphisms, form an additive category, so their isomorphism classes form a monoid. We study the quotient monoid of this monoid by the submonoid of isomorphism classes of free modules with component wise derivation ...
Lourdes Juan, Andy Magid
openaire   +2 more sources

Integrally closed modules and their divisors

open access: yes, 2018
There is a beautiful theory of integral closure of ideals in regular local rings of dimension two, due to Zariski, several aspects of which were later extended to modules. Our goal is to study integral closures of modules over normal domains by attaching
노선숙
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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