Results 51 to 60 of about 2,084 (272)
Moduli space of meromorphic differentials with marked horizontal separatrices
, 2020 Journal ref: Algebraic & Geometric Topology. 2020 (20)International audienceWe study framed translation surfaces corresponding to meromorphic differentials on compact Riemann surfaces, for which a horizontal separatrix is marked for each pole or zero ...
Boissy, Corentin
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Loci in strata of meromorphic differentials with fully degenerate Lyapunov spectrum
, 2013 International audienceWe construct explicit closed GL(2, R)-invariant loci in strata of meromorphic differentials of arbitrary large dimension with fully degenerate Lyapunov spectrum.
Hubert, Pascal +3 more
core +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Acyclicity of Schur complexes and torsion freeness of Schur modules
, 2019 Let R be a Noetherian commutative ring and M a R-module with pdRM≤1 that has rank. Necessary and sufficient conditions were provided in [1] for an exterior power ∧kM to be torsion free.
Alexandre Tchernev +3 more
core +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Differential modules and K-groups
Journal of Algebra, 1991 Having defined dlog and res maps, the author proves that the following diagram of abelian sheaves on \(X\) is commutative for all \(p>0\) with exact rows, where \(X\) is a smooth scheme over a field of characteristic 0, \(Y\) is closed subscheme of codimension one in \(X\), \(U=X-Y\), and the top row is the localization sequence of \(K\)-sheaves ...
openaire +1 more source
Torsion of differentials of hypersurfaces with isolated singularities
, 1995 Let R = K[X1,X2,…,XN], where K is an algebraically closed field of characteristic 0 and consider the reduced, affine hypersurface algebra with an isolated singularity A = R(F), where F ϵ K[X1,X2,…,XN].
Michler, Ruth
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
On the Rank of Multigraded Differential Modules
Michigan Mathematical JournalA $\mathbb{Z}^d$-graded differential $R$-module is a $\mathbb{Z}^d$-graded $R$-module $D$ equipped with an endomorphism, $δ$, that squares to zero. For $R=k[x_1,\ldots,x_d]$, this paper establishes a lower bound on the rank of such a differential module when the underlying R-module is free. We define the Betti number of a differential module and use it
Boocher, Adam, Devries, Justin W.
openaire +2 more sources