Results 1 to 10 of about 168,114 (189)

MOG-IgG associated optic neuritis is not multiple sclerosis [PDF]

Arquivos de Neuro-Psiquiatria, 2017
Autoantibodies against myelin oligodendrocyte glycoprotein (MOG-IgG) have been reported in patients with inflammatory central nervous system disorders including isolated optic neuritis (ON). We compared our MOG-IgG ON patients with multiple sclerosis (MS)
Bruna Klein da Costa, Giordani Rodrigues dos Passos, Jefferson Becker, Douglas Kazutoshi Sato   +3 more
doaj   +8 more sources

Recent developments in MOG-IgG associated neurological disorders [PDF]

Therapeutic Advances in Neurological Disorders, 2020
In the past few years, acquired demyelinating syndromes of the central nervous system associated with antibodies against myelin oligodendrocyte glycoprotein (MOG) have evolved into a new inflammatory disease entity distinct from neuromyelitis optica ...
Harald Hegen, Markus Reindl
doaj   +5 more sources

Positive Predictive Value of MOG-IgG for Clinically Defined MOG-AD Within a Real-World Cohort [PDF]

Frontiers in Neurology, 2022
Myelin oligodendrocyte glycoprotein antibody associated disease (MOG-AD) is a CNS demyelinating disease, typically presenting with optic neuritis, transverse myelitis, and/or ADEM-like syndromes.
Marcelo Matiello, Farrah Mateen, Michael Levy   +2 more
exaly   +4 more sources

Case report of intracranial tumor with serum MOG-IgG positivity [PDF]

Frontiers in Immunology
Objective To deepen understanding of the correlation between intracranial tumor and serum myelin oligodendrocyte glycoprotein immunoglobulin G (MOG-IgG) positivity, emphasizing the importance of avoiding misdiagnosis. Methods We report
Min Z, Wang L, Kang Y, Zhang L.
exaly   +4 more sources

Details and outcomes of a large cohort of MOG-IgG associated optic neuritis [PDF]

Multiple Sclerosis and Related Disorders, 2022
The goal of this study was to examine the temporal relationship of eye pain to visual loss and investigate whether timing of steroid treatment affects the rate and extent of visual recovery in optic neuritis (ON) from MOG-IgG associated disease (MOGAD) in a large cohort of MOGAD patients with ON.This is a multicenter, retrospective cohort study of ...
John Chen, Mark A Hellmann
exaly   +4 more sources

Optic neuritis of MOG-IgG-associated autoimmune disorders: a case report [PDF]

BMC Ophthalmology, 2021
Background The diagnosis of immunoglobulin G serum antibodies to myelin oligodendrocyte glycoprotein (MOG-IgG) associated inflammatory demyelinating disorders can be confirmed by the presence of MOG-IgG, yet its general cut-off concentration had not yet ...
Tiantian Li, Jian Zhou, Xiaoling Yan, Ran Duan, Xiaobo Zhu   +4 more
doaj   +5 more sources

Frequency of MOG-IgG in cerebrospinal fluid versus serum. [PDF]

J Neurol Neurosurg Psychiatry, 2022
Immunoglobulin gamma autoantibodies directed against myelin oligodendrocyte glycoprotein (MOG-IgG) are associated with specific neurological syndromes, most frequently acute disseminated encephalomyelitis, optic neuritis and longitudinally extensive transverse myelitis.1 For all neurological surface-directed autoantibodies, including MOG-IgG, serum ...
Pace S, Orrell M, Woodhall M, Palace J, Leite MI, Irani SR, Waters P, Handel AE.   +7 more
europepmc   +4 more sources

"Low-Positive" MOG-IgG Cases Among Adults With a First Event Suggestive of Multiple Sclerosis. [PDF]

Ann Clin Transl Neurol
ABSTRACT Objective To determine the prevalence and clinical characteristics of patients with “low‐positive” (LP) MOG‐IgG (titres 1:160–1:320) among adults with a first demyelinating event (FDE) suggestive of multiple sclerosis (MS). Methods From the Barcelona CIS inception cohort, we included adult patients with serum collected ≤ 6 months from the FDE.
Villacieros-Álvarez J, Espejo C, Arrambide G, Castillo M, Rodriguez M, Ariño H, Elosua I, Tur C, Vidal-Jordana A, Vilaseca A, Castilló J, Galán I, Midaglia L, Nos C, Rodríguez-Acevedo B, Zabalza A, Bollo L, Pappolla A, Carvajal R, Mongay-Ochoa N, Rio J, Sastre-Garriga J, Comabella M, Busiello G, Sceppacuercia S, Rovira À, Montalban X, Tintoré M, Auger C, Cobo-Calvo Á.   +29 more
europepmc   +2 more sources

The relationship between serum MOG-IgG titer status and titers and the prognosis of pediatric MOGAD: a retrospective cohort study [PDF]

Frontiers in Pediatrics
BackgroundTo explore the clinical value of MOG-IgG serum titer change and duration in predicting the relapse of MOGAD in children.MethodsThe clinical data, imaging data and laboratory examination results of 63 children with MOGAD were analyzed, and the ...
Mengfan Pei, Yuyang He, Shan Huang, Cong Yao, Jing Chen, Lanhong Xiang, Chunhui Yuan, Hongmin Zhu   +7 more
doaj   +2 more sources

Emerging drugs for the treatment of adult MOG-IgG-associated diseases [PDF]

Expert Opinion on Emerging Drugs, 2021
Myelin oligodendrocyte glycoprotein (MOG), a member of the immunoglobulin (Ig) superfamily, is a myelin protein expressed at the outermost lamellae of myelin sheaths and oligodendrocytes (OGD) memb...
Edgar Carnero Contentti, Mariano Marrodan, Jorge Correale   +2 more
exaly   +3 more sources