Results 1 to 10 of about 184,937 (258)

Pathophysiology of myelin oligodendrocyte glycoprotein antibody disease

Frontiers in Neurology, 2023
Myelin Oligodendrocyte Glycoprotein Antibody Disease (MOGAD) is a spectrum of diseases, including optic neuritis, transverse myelitis, acute disseminated encephalomyelitis, and cerebral cortical encephalitis.
Tanuja Chitnis
exaly   +6 more sources

Antibodies to myelin oligodendrocyte glycoprotein in optic perineuritis [PDF]

Frontiers in Immunology
IntroductionThis study aimed to investigate the prevalence of myelin oligodendrocyte glycoprotein antibodies (MOG-IgG) in patients with optic perineuritis (OPN) and to analyze the clinical characteristics and prognosis of MOG-IgG–seropositive cases ...
Shanshan Cao, Shanshan Cao, Yuan Zhang, Xintong Xu, Mingming Sun, Chunyan Pan, Yuhang Wang, Shihui Wei, Quangang Xu, Huanfen Zhou   +9 more
doaj   +5 more sources

Myelin oligodendrocyte glycoprotein associated disease

Journal of Clinical Ophthalmology and Research
Nikhat Iqbal Tamboli, Asma Farheen, Snehalata Yellambkar, Rajesh Subhash Joshi   +3 more
doaj   +3 more sources

Myelin-oligodendrocyte glycoprotein antibody-associated disease. [PDF]

The Lancet Neurology, 2021
Myelin-oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a recently identified autoimmune disorder that presents in both adults and children as CNS demyelination. Although there are clinical phenotypic overlaps between MOGAD, multiple sclerosis, and aquaporin-4 antibody-associated neuromyelitis optica spectrum disorder (NMOSD ...
R. Marignier, Y. Hacohen, Á. Cobo-Calvo, A. Pröbstel, O. Aktas, H. Alexopoulos, Mary Amato, N. Asgari, B. Banwell, J. Bennett, F. Brilot, M. Capobianco, T. Chitnis, O. Ciccarelli, K. Deiva, J. Seze, K. Fujihara, A. Jacob, H. Kim, I. Kleiter, H. Lassmann, M. Leite, C. Linington, E. Meinl, Jacqueline Palace, Friedemann Paul, A. Petzold, S. Pittock, M. Reindl, D. Sato, K. Selmaj, A. Siva, B. Stankoff, M. Tintoré, A. Traboulsee, P. Waters, E. Waubant, B. Weinshenker, T. Derfuss, S. Vukusic, Bernhard Hemmer   +40 more
semanticscholar   +8 more sources

Myelin oligodendrocyte glycoprotein antibody-associated optic neuritis and myelitis in COVID-19: a case report and a review of the literature

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2022
Background Our case explored the spectrum of autoimmune and infectious neurological complications of Coronavirus Disease 2019. In addition, we also reviewed and discussed clinical features, neuroimaging, CSF findings, and outcomes in patients with COVID ...
Mark A. Colantonio, Divine C. Nwafor, Shruti Jaiswal, Ashish K. Shrestha, Mahmoud Elkhooly, Steven Rollins, Sijin Wen, Shitiz Sriwastava   +7 more
doaj   +2 more sources

Epidemiology of myelin oligodendrocyte glycoprotein antibody-associated disease: a review of prevalence and incidence worldwide

Frontiers in Neurology, 2023
Myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD) is an inflammatory demyelinating disease of the central nervous system (CNS) with the presence of conformation-sensitive antibodies against MOG.
Kazuo Fujihara
exaly   +2 more sources

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease: A Comparison With Rituximab. [PDF]

Ann Clin Transl Neurol
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Fan Y, Zhou L, ZhangBao J, Tan H, Wang Z, Quan C.   +5 more
europepmc   +2 more sources

Early blood neurofilament light chain and myelin oligodendrocyte glycoprotein antibody levels associate with different disease courses of myelin oligodendrocyte glycoprotein-associated disease in children

Brain Communications, 2023
Acquired demyelinating syndrome associated with myelin oligodendrocyte glycoprotein antibodies, named recently myelin oligodendrocyte glycoprotein-associated disease, represents >27% of this paediatric syndrome.
Roger le Grand, Chretien Pascale
exaly   +2 more sources

The Structure and Function of Myelin Oligodendrocyte Glycoprotein [PDF]

Journal of Neurochemistry, 1999
Abstract : Myelin oligodendrocyte glycoprotein (MOG) is a quantitatively minor component of CNS myelin whose function remains relatively unknown. As MOG is an autoantigen capable of producing a demyelinating multiple sclerosis‐like disease in mice and rats, much of the research directed toward MOG has been immunological in nature. Although the function
Terrance Johns, Claude C A Bernard
exaly   +3 more sources

Quantitative MRI Uncovers Subtle Cortical Damage in Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease. [PDF]

Ann Clin Transl Neurol
ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Camera V, Tamanti A, Messina S, Dall'Osto N, Maltempo T, Ziccardi S, Foschi M, Piscaglia MG, Ferraro D, Crescenzo F, Rossi F, Bajrami A, Marangoni S, Marastoni D, Pizzini FB, Leite MI, Magliozzi R, Waters P, Calabrese M, Palace J, Geraldes R.   +20 more
europepmc   +2 more sources